PEDIATRIE PRO PRAXI / Pediatr. praxi. 2023;24(3):169-174 / www.pediatriepropraxi.cz 174 PŘEHLEDOVÉ ČLÁNKY Imunodysregulačné aspekty detí s Downovým syndrómom LITERATÚRA 1. Ni She R, Filan PM. Trisomy 21– incidence and outcomes in the first year, in Ireland today. Ir Med J. 2014;107(8):248-249. 2. de Graaf G, Buckley F, Skotko BG. Estimation of the number of people with Down syndrome in Europe. Eur J Hum Genet EJHG. 2021;29(3):402-410. 3. Ďurdíková V, Ďurdík P, Bánovčin P. Pridružené ochorenia u detí s Downovým syndrómom. Pediatr. 2008;3(6):338-342. 4. Huggard D, Doherty DG, Molloy EJ. Immune Dysregulation in Children With Down Syndrome. Front Pediatr [Internet]. 2020;8. [cit. 2022-03-07] Available from: https://www. frontiersin.org/article/10.3389/fped.2020.00073. 5. Lee YI, Peng CC, Chiu NC, et al. Risk factors associated with death in patients with severe respiratory syncytial virus infection. J Microbiol Immunol Infect. 2016;49(5):737-742. 6. Garrison MM, Jeffries H, Christakis DA. 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Down Syndrome and COVID-19: A Perfect Storm? Cell Rep Med. 2020;1(2):100019. 37. Hüls A, Feany PT, Zisman SI, et al. COVID-19 Vaccination of Individuals with Down Syndrome – Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated. Vaccines. 2022;10(4):530. 38. Cao C, Wang J, Li Y, et al. Efficacy and safety of OM-85 in paediatric recurrent respiratory tract infections which could have a possible protective effect on COVID-19 pandemic: A meta-analysis. Int J Clin Pract. 2021;75(5):e13981. 39. Marseglia GL, Benazzo M, Biasci P, et al. OM-85 in the prevention of respiratory infections: State-of-the-art and future perspectives in clinical practice. J Biol Regul Homeost Agents. 2021;35(3):847-863. 40. Luan H, Zhang Q, Wang L, et al. OM85-BV Induced the Productions of IL-1β, IL-6, and TNF-α via TLR4- and TLR2-Mediated ERK1/2/NF-κB Pathway in RAW264.7 Cells. J Interferon Cytokine Res. 2014;34(7):526-536. 41. Chia E, Clark A, Flynn B, et al. P549 Should children with down syndrome receive prophylactic antibiotics to prevent recurrent respiratory infections? Arch Dis Child. 2019; 104(Suppl 3):A373-A373. 42. Huggard D, Kelly L, Worrall A, et al. Melatonin as an immunomodulator in children with Down syndrome. Pediatr Res. 2022;91(7):1812-1820. 43. Saghazadeh A, Mahmoudi M, Dehghani Ashkezari A, et al. Systematic review and meta-analysis shows a specific micronutrient profile in people with Down Syndrome: Lower blood calcium, selenium and zinc, higher red blood cell copper and zinc, and higher salivary calcium and sodium. PloS One. 2017;12(4):e0175437. 44. Stagi S, Lapi E, Romano S, et al. Determinants of Vitamin D Levels in Children and Adolescents with Down Syndrome. Int J Endocrinol. 2015;2015:896758. www.pediatriepropraxi.cz Pediatrie pro praxi
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