621
www.pediatriepropraxi.cz3408040010765133201214264309359378418445472491535585612659709736777817836852893931
/35628040010732
Pediatr.3639804001074587137156196223250262
praxi.3921804001075077118158177193
2025;26(1):33-364134804001074487128172185229272295335352367411453480521565
/47448040010731
PEDIATRIE4821804001074588147168222260309330374
PRO5216804001074591154
PRAXI5391804001074692148201221
3356558020012657113
PŘEHLEDOVÉ4549200012660124182256312369444520587645
ČLÁNKY5216200012660115187259327395
Farmakologicky276736001062867102157197233271303342382399434470509
indukovaná32923600106155696137172211248285326366
gynekomastie367436001063774116148183222276317351383401433
u4122360010639
dětských417736001063769103135170209242283
pacientů:447636001063269102120152193225267282
Přehled477336001063368100141173205245
nejčastějších50333600106397198133174208241273300332349383424
léků54733600106296197138
Farmakologicky3407800298126243332536662790923988112512651329143515651695
indukovaná208478002986620534648461274686899311311256
gynekomastie3388780029814026640653166179499911251227131313791504
u34010400298140
dětských52810400298143269356460589719823963
pacientů:153910400298144269375440564705790929988
Přehled257610400298139227353493557682825
nejčastějších3450104002981402653324395656677538789451048111212171357
léků48561040029866191321460
MUDr.3401440013793168245287310
Júlia6721440013746110140170228
Bartková,9221440013767125167209270332388446476
MBA,14201440013793160231262
MPH1,17041440013793158232193214500803651
2,199614500803620341440013729
Joachim20851440013745109167216281311405
Pilin3,2513144001376393123153217272914500803627661440013729
Jan28171440013745103167
Tkáč2,30061440013761120179228323414500803632721440013729
Marianna33231440013793152193223281345410467
Kotradyová2381314400137671281692122693353924555115694381145008036
1Klinika340160007833371160001336087111172197247301
popálenin6951600013363124186240265320381406466
a11841600013353
plastické1260160001336389141184221246294345398
chirurgie,16821600013349109134169230265326351405427
FN21321600013354124
Brno2279160001336095156216
2Lékařská3401750078333731750013352106158211246290341395
fakulta791175001333286136197222258311
Masarykovy11261750013388141184237272327379438489544
univerzity16941750013360121146198252288336362397452
Brno2169175001336095156217
3III.34019000783337419000133265278102
lékařská499190001332681132186221265316369
fakulta892190001333285136196222258311
Univerzita12261900013371131156209262298347372408461
Karlova17111900013359113148174234286338
Praha2073190001335893146206258
Gynekomastie3402390012165109163211257308390436473505526574
je929239001212472
benigní10162390012157106160181235288309
zvětšení1340239001214391138170208257310331
prsní1686239001215788126179200
žlázy1901239001214364110151199
u21152390012155
mužů,21852390012183136177230249
které2448239001214781128159207
může26692390012184137177225
mít29092390012183104136
významný3059239001214897140193239321374417
psychologický3491239001215794140182235288340253001212478133155198243292
dopad,6562530012157111167214269288
zejména969253001214392114196245300346
u13402530012156
dětí14202530012157106138159
a16042530012148
adolescentů.16772530012149104158180229267311358413443497516
Tento2217253001215093147178230
článek2472253001214567113167216262
se2759253001214089
zabývá2872253001214392147192242290
farmakologicky3186253001213077108191238283335357411467488531576625
indukovanou340267001212478133187232284330377431485539
gynekomastií9042670012157103158207253306389435473505527548
a14772670012149
nejčastějšími15512670012156105127171218256288336358395417499521
léky,2097267001212473119168182
které2304267001214782130161209
mohou25382670012184138193247301
přispět2864267001215789111148203253285
k31742670012147
jejímu324626700121247396117200253
vzniku.3524267001214992146168213267287
V3402810012156
rámci412281001213279160203224
naší6522810012156102139160
analýzy8282810012148101147168214257305
jsme1149281001212461142191
identifikovali1356281001212378126180210231258282327379424470492513
a18852810012148
přezkoumali1949281001215788135177222273327408454475496
relevantní2461281001213381103151197243296327380401
studie2878281001214072124179200248
a31422810012149
kazuistiky3207281001214694135188209246278299344392
publikované3615281001215711016534029500121244489140185231284332
v6862950012148
databázi7482950012156102132178233279320342
PubMed,11032950012153105160238287342360
které1477295001214780127158205
se1696295001214088
zabývají1798295001214290144188238284305326
různými2138295001213386126180223305326
aspekty2477295001214885139188233267314
gynekomastie28052950012156101155203248300381427464495516564
u33832950012155
dětských34512950012157105136174218266308360
pacientů.3403090012157104146167216269300352371
Důležitým7293090012166119140189230251282330412
krokem1159309001214779132177224306
v14823090012148
prevenci1548309001215788136181229282325346
gynekomastie19123090012156102156204250301383429466498519567
je2497309001212473
informovanost2587309001212477104157188270323368414468521558590
zdravotnického3195309001214397127174218270301354375418463510563616
personálu,3403230012156105135173225278323344396414
rodičů768323001213284138159201252
a10343230012147
pacientů10953230012156102144164212265294346
o14553230012154
potenciálních15223230012157110140187239282302347368420441483535
rizicích207032300121335494115157177219271
spojených2355323001213992146167214267310351403
s27723230012139
užíváním2824323001215595116161207259280360
určitých3197323001215585126147177224265318
léků.3528323001212371115168186
Je3727323001213784
nevyhnutelné,3403370012155102146194247299350380427448500547564
aby9173370012147101144
při1074337001215686107
předepisovaní1194337001215686132186233287308344396440485537557
léčby1764337001212371113166210
byly19863370012156100121166
zohledněny2164337001214394147167214268320368420462
veškeré2639337001214894130174219249296
možné29483370012182134173225272
vedlejší3233337001214894148168215237272293
účinky,3538337001215597117169212259273
a3403510012148
aby4023510012148103147
se563351001213987
provedlo664351001215788140185232287309362
důkladné10393510012157109153176222277330378
zhodnocení1431351001214296149204257310353400453474
poměru19193510012157111192241271324
přínosů2257351001215788109162215252304
a25753510012148
rizik.263735100121335495116160181
Mimo28323510012180102183236
jiné308235100121244598146
se3242351001214088
doporučuje33443510012156109164218248302344397419467
provádět340365001215788140186232287335366
pravidelné729365001215788134179201255303325378427
kontroly1178365001214799153183214266288334
a15343650012148
hodnocení16053650012155108164217270314361414435
pacientů,20633650012157104146167215269299352371
kteří2457365001214780128158180
užívají2659365001215596118164210232253
rizikové293536500121335495116161213258305
léky,3262365001212472117166180
aby34643650012149103148
bylo36343650012157102124177
možné3403790012183135174227274
včas628379001214788134170
identifikovat811379001212477125177207228254278322373417463492
a13173790012147
řešit1378379001213279116136166
případné1558379001215686107161207261313361
příznaky1932379001215686107147200245289336
gynekomastie.22823790012155100153201245296377422458490510557575
Tento2870379001214990143173224
článek3107379001214565110163210255
zdůrazňuje3375379001214296147177223264316368389436
potřebu3403930012157111142172220275328
zvýšené683393001214392140178226280328
pozornosti10263930012157111150203234288341378410431
k14723930012146
vybraným1533393001214897152183230283327409
lékům,1956393001212472118171252271
které2241393001214781128159207
jsou2463393001212461114167
nejčastěji26453930012155104126168215252284331353374
uváděny30343930012155101148202250304347
v33963930012148
odborné34593930012155110165219249303352
literatuře,34040700121244576123154200231284314362380
a7374070012148
multidisciplinární8024070012183136158189210264285322365386441463484537583613667688
přístup1507407001215788110146178231286
k18104070012147
léčbě.1874407001212372115170219236
Informovanost2127407001212477104157188270323368415468521558590
o27344070012155
farmakologických2806407001212976107188234279331353406461482525569617659712
rizicích353540700121335595117159180223276
a3404210012148
podpora4004210012156109163217269299345
ze758421001214289
strany86042100121396999145197239
zdravotnických1112421001214295125170214264294346367408452499540592
odborníků17164210012154108162215245297318363415
jsou2144421001212460112164
klíčové232142100121466888130180224270
pro2604421001215686138
prevenci2754421001215787133178224276318338
a31054210012148
zvládnutí3165421001214390112156210262313344364
tohoto3542421001213283136188218269
stavu,340435001214071118163217235
ale592435001214869118
také726435001213380125171
pro914435001215788140
psychologickou1071435001215794140182235288310363418439482526578631
pohodu17194350012157111164218273325
dětských20614350012156104136174219267309362
pacientů24394350012157104147168216270300353
trpících2808435001213364119141183204247300
touto3124435001213385139170222
diagnózou.3362435001215778124178231284324377430449
Klíčová340451001246291119165223275329
slova:696451001244473131184238263
gynekomastie,9874520012156105162213260315399448487522545596616
benigní16324520012157109165188245301324
zvětšení1985452001214394144178219270326349
prsní2363452001215791131187211
tkáně,2602452001213481130186237257
dětská28884520012157108141182229279
gynekomastie,31964520012156105161212260314399448487521545595616
léky340466001212474121171
indukovaná533466001212378135190236290337386441489
gynekomastie.10434660012156104160211258311395443482516539589609
Pharmacologically3404880012458116169207294347392450478536595623668722750778830
induced1191488001242786146204250303363
gynecomastia15744880012459112172225271328415468512549577630
in2225488001242786
pediatric23314880012460113174202255291331358403
patients:27554880012459113149178231290327371397
a3405020012453
review413502001243891144172225301
of734502001245892
the847502001243696149
most10165020012486145188225
common12625020012445102189275333392
medications16745020012486140200228273327364392450509552
Gynecomastia3405190012165111167217263316400448487520543591
is949519001212362
a10295190012148
benign10955190012157108163186242297
enlargement14105190012150106129177209265315398449504537
of1965519001215483
breast2066519001215790140188227260
tissue234451900121335695134188238
in2600519001212479
males26975190012183131154205244
that2959519001213388136168
can3145519001214594149
have33125190012155103149198
significant3528519001214063118174197226252340533001214492147178
psychological536533001215695142185239293317371427450494542564
impacts,11185330012123105161209253287327348
especially1483533001215088144194239262309332354401
in1901533001212378
children1996533001214498121144199231280335
and23485330012148102158
adolescents.25235330012148104158182231270314363417449489510
This30505330012149105127165
article3232533001214880115138182204254
focuses3503533001212983128182220270309
on3405470012155112
pharmacologically4805470012158114163196280329374429453509566590635684708731779
induced1288547001212479137192237287345
gynecomastia16625470012156104161212259313397446485520543591
and22825470012149105162
the2473547001213389140
most26415470012185140180214
common28845470012145100184268324380
medications32935470012184135193217262311344367423479518
that340561001213388136169
may5305610012183131177
contribute728561001214598154186219243299355388437
to1186561001213387
its129456100121245797
development.14125610012157107155204228283340424474530562583
In2016561001212480
our21175610012155110142
analysis,22805610012149104152175223262285324345
we26465610012174123
identified2790561001212380130186218241271297347404
and32155610012148104160
examined3396561001215098146229252308358415
relevant340575001213383108159207256312344
studies713575001214074130187211262302
and10435750012149105162
case1234575001214594134185
reports1447575001213384141198231268309
published17855750012157113170195218257313364422
in2236575001212379
the2344575001213389140
PubMed25135750012154108166247299357
database28985750012157106139188246295335386
that3312575001213489138171
discuss3512575001215780119165220260299
various340589001214897129153208263302
aspects664589001214887143195240276316
of1002589001215584
gynecomastia11085890012156104160210256310393442481514537585
in1715589001212479
pediatric18165890012157108165188236269301325369
patients.22075890012157106138161212267300340361
An25905890012162117
important27295890012123106163219252288337392424
step3175589001214074123180
in3377589001212378
the3477589001213389139
prevention3638589001215790140340603001214897153185208263319
of685603001215484
gynecomastia7946030012156104160211256310394442481515538585
is1405603001212362
the1493603001213388139
awareness16576030012148121169202251307357397436
of2119603001215584
healthcare22286030012156106154178211266311359392442
professionals,2695603001215790145174224263303325380436484508546567
parents,32886030012157106138188244276316338
and36516030012148104160
patients3406170012157106138161211267299340
regarding699617001213382139187220276299354410
the1128617001213388139
potential12866170012157113145195250283306354377
risks168261700121325695141184
associated1885617001214887126181227250297330379436
with2340617001217498131186
the2545617001213388138
use2702617001215594145
of2866617001215584
certain2969617001214594126162211234289
medications.32776170012184134192215259308341364419474513534
It340631001212457
is415631001212362
essential495631001215089128179234267290337361
that874631001213388136168
all106063100121487295
possible11736310012157112152191214270294344
side1535631001214063119169
effects1722631001215080113163208244284
are2024631001214881130
considered2172631001214599154193216272322355405462
when26526310012174129180235
prescribing2905631001215790140179224257280337360416472
treatment3395631001213365115163195278329384417
and3406450012148103159
that516645001213388135167
a7016450012148
thorough766645001213388142175229284339394
assessment1177645001214887126176215253336386441473
of1667645001215584
the1768645001213388138
benefits19236450012157107162212242267300340
and22816450012148102158
risks245764500121325694140182
is2656645001212462
conducted.2736645001214497152208263307342391448468
Additionally,32226450012160116172195227250304360407430453500516
it3755645001212356
is340659001212362
recommended423659001213383128182266349400455512562619
to1064659001213387
carry1172659001214593126159209
out14026590012155110143
regular1567659001213282139194217265298
check-ups1886659001214499150196242270327383423
and23306590012148103160
evaluations2511659001215098146170224272305328383439477
of3010659001215483
patients31156590012157105138161211267299340
who34766590012173129184
are3681659001214881131
taking340673001213380126150204258
high-risk615673001215577132185217249272310355
medications9876730012182131187210253301332354408462500
to1504673001213285
identify1606673001212378127181213235263313
and19366730012147101156
address21096730012147103158190238276314
any24406730012148102146
symptoms2603673001213986168223256308390428
of3048673001215482
gynecomastia31476730012155101156205250302384431469502524571
in3734673001212377
a3406870012148
timely406687001213356139190214261
manner.6856870012183131186241292325341
This10446870012150106129167
article1229687001214981117140184207258
emphasizes15056870012150133190246293332355398448487
the2010687001213388139
need21676870012155105156214
for2399687001212984116
increased2533687001212479124156206254293343400
attention2951687001214881116165221253276331387
to3356687001213386
selected3460687001214090114165210245295352
medications3407010012184134192215260309342365420476515
commonly883701001214599183267322378402449
cited1361701001214468101150208
in1597701001212479
the1704701001213489140
scientific1872701001214085108158214247270300326371
literature227170100121244780130163211244299332382
and26817010012149104161
a28707010012149
multidisciplinary29477010012184139162195218275299337383406463487510565614646697
approach36727010012149105340715001215688142189233287
to644715001213386
treatment.747715001213264113160192273323378409430
Awareness11947150012160130178209258313362401439
of1650715001215482
pharmacological17497150012156111158190272319363416439493549571615662685
risks245171500121325593139180
and26487150012148102157
support2822715001213993148204259291326
from3165715001212962115197
healthcare33797150012155105152174207261305352384433
professionals340729001215789143172221260299321376431478501540
are897729001214880129
crucial1044729001214476131175198245268
for1330729001212983116
the1463729001213387137
prevention1618729001215689138185234289321343397453
and20887290012148103159
management22647290012183130185233288338421471526558
of2839729001215583
this2940729001213387110148
condition,3105729001214598153209232264287341397417
as3539729001214887
well36437290012173122146169
as340743001214887
for444743001213084117
the579743001213387137
psychological734743001215796144187242297321375432455499547571
well-being13227430012174123147170201259310333388444
of1783743001215584
pediatric18857430012156107164187234267299322367
patients22697430012157106138161210266298338
suffering2625743001213993123155205237261316371
from3014743001212962117200
this3232743001213387110149
diagnosis.3398743001215679127183238292331354393414
Key3407600012461111162
words:5187600012475131168228271296
gynecomastia,8307600012155102157207251304386433472505527574594
benign14417600012156107161183238293
breast1751760001215688137184222255
tissue202376000121335593131185234
enlargement,22747600012149104127174205260309391441495527547
pediatric28387600012157107163185232264296319362
gynecomastia,32177600012156102158207252304387434472505527574595
drug-induced340774001215689144200232257312369423468517574
gynecomastia.9367740012156103160210256310393441480514537585606
DECLARATIONS:4068241008648871301662142563043393604124625014570241008514
Declaration406825500874987120141179206244271291333375
of445725500874066
originality:45372550087406888130150192230251271298337356
The406826600853473109
manuscript418826600855891130168195227249266306329
is452826600851744
original45832660085386178117133172205222
and481626600853472112
has49392660085387299
not50502660085387699
been516126600853975110149
published532226600853977117134150177216251291
or406827700853862
submitted414527700852867108167184208234269310
elsewhere.44702770085355381117169209245269305320
Ethical406829100873764107127160198218
principles43002910087427090132165185228249287319
compliance:463329100873173134177197218256298330368387
The406830200853678116
authors420530200853475100142183208238
attest44643020085356087124153179
that466430200852465101126
their481130200852465103121146
study49783020085295595138173
was517230200855490119
approved531230200853577120145186221258301
by406831300854073
the41583130085236399
local42743130085175689124141
Ethical44323130085345898115147182199
Committee464831300854179139198215239265300337
and500231300853373113
is513231300851745
in519431300851656
compliance526731300853169129169187204239278311346
with40683240085537298140
human423632400854081143180221
studies44863240085285596139157195226
and474032400853577119
animal48883240085347695156193212
welfare512832400855391110133170196234
regulations53903240085236110414516420140683350085234080120148
of423533500853960
the43153350085236399
authors’44343350085347397136176200229244
institutions46983350085165684109126150189213231270310338
as505633500853462
well513833500855187104122
as527933500853462
with53613350085526993133
the55143350085236299
World406834600856099124142184
Medical427334600855795137155188224242
Association453534600854474104144178196231256273314355
Declaration491134600854785119136172196232257274315356
of528834600853961
Helsinki537034600854684102131149189224243
on406835700853878
Ethical41653570085355898115147182199
Principles43833570085376178117150167207225261290
for46923570085205983
Medical479435700855693134151183218235
Research504835700853874102139173197229268
Involving53353570085175690128146181198238278
Human406836800854685145179219
Subjects430736800853474114132168201227256
adopted458336800853474114155179215256
by485836800854074
the49523680085236399
18th507136800853669514136800501437
WMA5198368008559116160
General537836800854582122158182217235
Assembly406837900854475105143204247266302
in439337900851758
Helsinki,447437900854785104134152193228248264
Finland,47613790085355394113149190232249
in503337900851758
June511537900852667109147
1964,528537900853771110150166
with54743790085537297139
subsequent406839000852867107136172213252288328352
amendments,443739000853493130169210269305345369398414
as486839000853462
well494839000855287105122
as508839000853362
with51673900085526993133
the53183900085236298
ICMJE543439000851759116143179
Recommendations406840100853977112153216278317359402439465483525568598
for46974010085226389
the481840100852466104
Conduct,495440100854283125168210245272290
Reporting,527540100853978121163189217236278321338
Editing,40684120085347491115132172212227
and430841200853373113
Publication443441200853776117134151183218242259298338
of478541200853859
Scholarly485741200853467106146163198221239273
Work514241200856097121155
in531041200851656
Medical537841200855693134151183218235
Journals,406842300852666105129169204221249265
updated435342300853980121155179215256
in462942300851656
December470542300854683116151211252289313
2018,503742300853673107140156
including52134230085165689106145186203243283
patient55164230085407540684340085234076116140
consent422243400853270110138174214238
where447543400855191127151187
appropriate.467743400853474115139178219243260295318354369
Conflict406844800874282124149171191223251
of433444800874065
interest44134480087196288126154192224251
and467844800873779122
financial48144480087244587125167200220258279
disclosures:51074480087416293126147188220261289327359378
None.406845900854686126162177
Funding/Support:406847200873777119162183225267291329371414457499526554574
None.406848400854686126162177
Cit.4068714008541588297
zkr:41807140085306489105
Pediatr.429971400863975117136173198224238
praxi.455271400864067103139158176
2025;26(1):33-36474371400863775112150167205243264300317334373409433470508
https://doi.org/10.36290/ped.2025.007406872500853962881291571721982194284725008641811004385725008514547811714345287250086387390130169206244283307347385427445485523560598615654693730
Článek40687360085415892132168202
přijat4285736008539638198132156
redakcí:445673600852359100134168199216231
4.470173600853652
11.47677360085366679
2024486173600853572107141
Článek40687470085415892132168202
přijat4285747008539638198132156
k4456747008533
tisku:45047470085234068101141156
20.46757470085367287
1.477774700853548
2025484074700853572107143
MUDr.4068766008759108158186202
Júlia42847660087297191112150
Bartková,444876600874280108136176216254292311
MBA,4773766008760104150170
MPH4958766008759101150
jul.bartkova@gmail.com4068778008517567389130165189215248287321356408449508543560577592624663722