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bradavic52936001063369111151189224241276
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bradavic10139200298143233357498623744808915
u19769200298140
dětí21659200298143268356422
MUDr.3401320013793168245287310
Helena6721320013776135166224289347
Michalíková10411320013793124173238296326356417480536594
Dermatovenerologie,3401480013373129165256309344403454508569624659719745805867892947968
Canadian13321480013363116177229291316368428
Medical,17841480013388143206231280333358380
s.2187148001334467
r.2268148001333653
o.,2335148001336081105
Praha2463148001335893146206259
Virové340199001215578108160204251
bradavice605199001215687133187233277299341388
jsou1007199001212460113166
celosvětově1187199001214491113165202249295326378423469
časté1670199001214591127159206
onemocnění18901990012154107155236289332385432486506
způsobené2411199001214296149186238293342395443
lidským286819900121234498135179226308
papilomavirem,31901990012156102157178199252333378423444475522603621
který340213001214781129160209
má5732130012183130
řadu726213001213380135188
genotypů.9372130012156105159213244293349403422
Mnoho13822130012180135188243296
z17022130012142
těchto1768213001213381125178209261
virů2053213001214870101155
je2231213001212574
komenzálních2328213001214799181230284326374396450471514568
a29192130012149
u29912130012155
imunokompetentních30692130012124106159213266312364446502551583631685716340227001215677120174
hostitelů5392270012155109147179201232280303356
nevyvolávají9202270012155104150200250302325371416463485507
žádné1452227001214391146200249
projevy.1726227001215789142164213259308323
Za20742270012156103
vhodných22022270012149103157212266310352406
podmínek26332270012157112167249271325374419
některé30772270012156105150185233264312
způsobují3414227001214399153190244299353376397
klinické34024100121477092146167210255303
změny6592410012143125174228272
na9482410012156102
kůži10672410012147100142164
nebo12472410012156105160215
na14792410012155102
sliznicích159724100121406283125179200243265308361
v19752410012148
anogenitální20402410012148102156211260314335367414436490511
či2568241001214566
orofaryngeální2651241001215586139167215245294349404453499521575596
oblasti.32642410012155110133180217249271290
U35712410012165
dětí36522410012157106137159
se340255001214089
nejčastěji4442550012155104126169216254286334356378
setkáváme837255001213988120165213258305386435
s12872550012140
verruca1342255001214896127159212256303
vulgaris,16602550012148102124179225256278316335
verruca2010255001214896127159212256303
plantaris2328255001215780126180210258289311348
a26912550012148
verruca2754255001214896127159212256303
plana.3072255001215780126180226246
Řada33332550012153100155202
těchto3550255001213380124178209261
projevů340269001215687140162210255309
samovolně663269001213986167220265317339392440
vymizí,1117269001214897178200240262280
problémem1412269001215687140194217265346394476
jsou1902269001212461114167
perzistentní20832690012157106137179201237269316370400453475
či2572269001214465
úporně26522690012154109163193247295
recidivující2962269001213280123144199220266320342363405426
bradavice.3403269001215687133188234278300343390408
Léčbou340283001214694136190243296
se650283001213986
snažíme750283001213991137177198278326
nejen10902830012155102124172224
zlikvidovat132828300121426484128177198252304349395425
viditelné1766283001214869123144175221243295343
změny21232830012142122170222265
za2402283001214289
minimalizace25052830012182103156176256302323344384431473519
bolesti30382830012156109131179216247268
a33202830012147
bez33812830012156104145
jizvení,354028300121244585133179232253271
ale340297001214870119
také477297001213381126173
o6682970012155
prevenci741297001215789137183231285328350
recidivy1109297001213381125147202223270319
ať1447297001214879
již154529700121244687
v16502970012148
místě17162970012184105143175222
původní19572970012157110157210265319341
bradavice2316297001215788135191237282304348395
nebo27292970012156105160215
kdekoli29622970012147101149195247270291
jinde327229700121244699154203
na34932970012156102
těle.3614297001213380103152170
Klíčová340313001246189116160217268321
slova:677313001244370128179231256
human9513140012155109191238293
papilloma12613140012156104160183206229283365413
virus,1691314001214871103157196216
keratinocyt,1924314001214795127175207229284338383432467488
verruca2429314001214896128161215260308
vulgaris,27543140012147102125180228260283321341
verruca3113314001214796128160215259307
plantaris,3437314001215680127182213261293316354375
verruca340328001214897130163219264312
plana,673328001215781129185233254
kyselina948328001214797136187211234289337
salicylová,1306328001214089112135180230254309356405426
kryoterapie.1753328001214781131185218267300349405429479499
Treatment340355001245587141194231318371431467
of827355001245893
warts9403550012476129167206250
in1210355001242887
children13173550012445104132160220258312371
Viral340373001215680112160183
warts5503730012174122154189230
are806373001214981130
a9633730012149
common1038373001214699182266321376
disease1441373001215779117167215254304
worldwide17723730012174128160183239313336392442
caused2241373001214593148186236293
by25613730012157103
the2691373001213488138
human28563730012156110194241296
papillomavirus,31793730012157106162185208230285369417463486518573612632
which3403870012174128150194248
has6123870012155102140
a7763870012148
number8483870012156109191247297329
of1201387001215583
genotypes.13083870012156105160214245294351401440460
Many17923870012180128182226
of2042387001215583
these2149387001213387137175224
viruses2397387001214871103157195244283
are2704387001214879128
commensal2856387001214597180262312366404452474
and33543870012148103158
do35363870012156110
not36703870012156110142
cause340401001214592146184233
any5894010012148102147
symptoms752401001213986169225257310393430
in1198401001212478
immunocompetent12924010012123105187241295349394446529585635667715770801
hosts.21094010012155109148180220240
Under23654010012165119174223255
appropriate26364010012148104160192245301333356402434482
conditions,3134401001214597152207230262283337392430450
however,36004010012155109181340415001215097145177192
some549415001214094177226
cause793415001214592146184233
clinical104441500121446789143165209256279
changes1340415001214599146200255305343
on17014150012155109
the1828415001213387136
skin1982415001214085109163
or2163415001215486
mucous22674150012183137181234288326
membranes26114150012183133215271303350405454493
in3121415001212478
the3216415001213388137
anogenital33704150012149103157213262317339371419441
or340429001215587
oropharyngeal449429001215587141197252299330379435490539586609
part.10804290012157105136171191
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vulgaris,16274290012149103126181228259282320340
verruca1989429001214896128160215259306
plantaris2318429001215780127181212260292314352
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verruca2873429001214896128160214258306
plana3201429001215780127182229
are3452429001214880128
most36034290012183137176208
often340443001215583118167221
encountered5844430012150104148201255310341389421470526
in1133443001212377
children.1233443001214599121143199230279334354
Many16094430012181128182227
of1858443001215583
these1964443001213387137175225
manifestations22114430012183131185207235284323356404435457511566604
disappear2837443001215679116164220276326373405
on32644430012155110
their3396443001213488137160191
own,36104430012154126181201
the340457001213387137
problem493457001215789143199222271354
is864457001212361
persistent9424570012157107139178200238271319373405
or1364457001215486
stubbornly1467457001214073127182238293325380403449
recurring1933457001213381126180211243266320375
warts.23254570012174121152187227247
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the2800457001213387137
treatment,2953457001213365114161192274324379410430
we34004570012174122
try3539457001213365114
not36704570012155109141
only3404710012154108130176
to531471001213385
eliminate63147100121497293174196249295326374
visible1020471001214770107128183205254
changes1289471001214498144197251300338
while16424710012173126148170218
minimizing18754710012183105158179260282323345398452
pain23434710012156103124178
and25364710012148101156
without2707471001217395126179233286318
scarring,3040471001213982129160191213267321340
but33954710012156110141
also3552471001214769106160
to3727471001213285
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recurrence,665485001213380124176207238285339382428447
whether11264850012173126175206259307338
at1479485001214778
the1571485001213386134
site172048500121396091138
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the1969485001213385134
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wart24344850012173119149183
or2632485001215485
anywhere27324850012147100144218271320350398
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on33164850012154108
the3438485001213386134
body.35874850012156109164210224
Key3405010012461113164
words:5235010012476133171231275301
human8445020012155110193242297
papilloma11605020012157106162186209232288371419
virus,1599502001214872104160199220
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verruca2401502001214897130163219264312
vulgaris,27335020012148103127183231263287326347
verruca3099502001214897130163219264312
plantaris,3431502001215781129184216265298321360381
verruca340516001214897130163219264312
plana,673516001215781129185233254
salicylic948516001213988112135179229253276321
acid,1290516001214893116173193
cryotherapy.1504516001214578128182215270321353402459505521
Virové400552001095072101149191235
bradavice651552001095080123174217258279319363
jsou1030552001092156105155
velmi1200552001094387108182203
časté1419552001094083118148192
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papilomavirem2866552001095094145166187236310353395416445490564
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papilloma4005630011254102157182207233285364412
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HPV),107456300112621151731249564001092643
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se1525564001093681
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„4006150010067
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skupina1028614001093678128180201251295
dsDNA1342614001095186146206261
virů162261400109446595145
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acid),3146614001094384105156182199
bez3364614001095198137
obalu35206140010950101146167217
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tvoří831626001093076125155176
cirkulárně102662600109406291134184205249279329375
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dvouvláknová1888626001095195144194238260304346398447490534
DNA24416260010960120175
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a16486500010943
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oblasti21226500010950102124167203234255
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L1,254266200109428195
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533469662001094689
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téměř1139674001093075151198227
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a17337460010943
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of445721500874066
originality:45372150087406888130150192230251271298337356
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adopted458332800853474114155179215256
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18th507132800853669514132900501437
WMA5198328008559116160
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in439333900851758
Helsinki,447433900854785104134152193228248264
Finland,47613390085355394113149190232249
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1964,528533900853771110150166
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as486835000853462
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as508835000853362
with51673500085526993133
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ICMJE543435000851759116143179
Recommendations406836100853977112153216278317359402439465483525568598
for46973610085226389
the481836100852466104
Conduct,495436100854283125168210245272290
Reporting,527536100853978121163189217236278321338
Editing,40683720085347491115132172212227
and430837200853373113
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Work514237200856097121155
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Medical537837200855693134151183218235
Journals,406838300852666105129169204221249265
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in462938300851656
December470538300854683116151211252289313
2018,503738300853673107140156
including52133830085165689106145186203243283
patient55163830085407540683940085234076116140
consent422239400853270110138174214238
where447539400855191127151187
appropriate.467739400853474115139178219243260295318354369
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interest44134080087196288126154192224251
and467840800873779122
financial48144080087244587125167200220258279
disclosures:51074080087416293126147188220261289327359378
None.406841900854686126162177
Funding/Support:406843300873777119162183225267291329371414457499526554574
None.406844400854686126162177
Cit.4068715008541588297
zkr:41807150085306489105
Pediatr.429971500863975117136173198224238
praxi.455271500864067103139158176
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Článek40687370085415892132168202
přijat4285737008539638198132156
redakcí:445673700852359100134168199216231
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tisku:45047480085234068101141156
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MUDr.4068767008759108158186202
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Michalíková452476700875980113155193213234274315352390
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