568
www.pediatriepropraxi.cz3408040010765133201214264309359378418445472491535585612659709736777817836852893931
/34708040010732
Pediatr.3547804001074587137156196223250262
praxi.3829804001075077118158177193
2025;26(4):253-2564042804001074487128172185229272295337358373417461503530569613656
/47438040010732
PEDIATRIE4821804001074587147168222260308330373
PRO5216804001074591154
PRAXI5391804001074591148201221
25356558020012657114171
KLINICKORADIOLOGICKÁ38422000126651211532262603233914635286006737077838399139861020108311501223
DIAGNÓZA5086200012671104174244318394454525
Streptococcus20753600106316399131166198237272311346379420452
agalactiae254336001063876116147189222256274314345
jako29043600106226196135
příčina30553600106336886120138179219
flegmóny32893600106296092132186226268305
měkkých361036001065183119155194227268
tkání389436001062965107148166
kotníku407636001063372102144161197238
novorozence433036001063980117157192233264296338373405
v4750360010636
důsledku480236001063879111141174214249291
Guthrieho510836001063778110151187205236277318
testu54423600106306296129170
Streptococcus34093002971222042924105456287598639961099120213351435
agalactiae181993002971332663984615936967818449761095
jako2963920029870195323457
příčina34699200298143233296402467606730
flegmóny42489200298811492744146197568951014
měkkých34011800298206332462594724828968
tkání13561180029888218345483547
kotníku195211800298130263350491555687826
novorozence282711800298140277399532621759869994113412411364
v34014400298127
důsledku51614400298143281384449574716845984
Guthrieho1548144002981643043905316206838089491085
testu26821440029888212316402541
prof.3401840013766108171209235
MUDr.5971840013793168245288311
Vladimír9301840013770100159224254349379421
Mihál,13731840013793124188246276305
CSc.1,17001840013766125175205189818500803651
2,196218500803619991840013729
MUDr.20501840013793168245287310
Lenka23821840013756115180239298
Bakaj-Zbrožková,27021840013766125184243273310371436478541593654716772830859
Ph.D.3,35841840013764127156234260384718500803638841840013729
MUDr.39351840013793168245287310
Kamila42671840013768126220251281339
Michálková3,46281840013793124173238296326386448505562518918500803652261840013729
Mgr.3401990013793158200223
Pavla5851990013764121177207265
Kučová,8731990013767129179242299356386
Ph.D.4128119900137641271562352601543200008036
1Ústav3402150078333712150013371113150203254
molekulární6482150013392152178233284345370422458519543
a12152150013353
translační1291215001333672125185227252305353414438
medicíny,17532150013392147209234283308368418435
LF22112150013352105
UP23392150013371129
a24922150013353
FN25682150013354124
v27152150013353
Olomouci27912150013376103163254315375424449
2Dětská3402300078333732300013373128165209260313
klinika,710230001335178103163188239293315
LF10492300013352104
UP11772300013371129
a13292300013353
FN14062300013353123
v15522300013353
Olomouci16292300013375102162254314374423448
3Radiologická3402450078333742450013359112174199259285345407432481531585
klinika,982245001335279104164189240294316
LF13222450013352104
UP14502450013371129
a16022450013353
FN16782450013354124
v18252450013353
Olomouci19022450013375102162254314374423448
4Ústav3402600078333742600013371113150203254
mikrobiologie,6512600013392117167205264326352412438498560585640662
LF13362600013352104
UP14642600013371129
a16162600013353
FN16932600013353123
v18402600013352
Olomouci19162600013376102162254314375424448
Odběr3403110012169126183234267
krve630311001214681132181
z8333110012143
patičky8993110012157106138161206252302
u12243110012155
novorozenců13023110012155111158212244299341391446491546
je1871311001212474
běžná19683110012157108151207255
metoda22453110012184134168222279327
používaná25953110012157113168211234282331386434
k30523110012147
odběru31213110012155113169220253308
kapilární3452311001214796153176200248280336359
krve340325001214781132181
na5443250012156104
novorozeneckých6713250012155111158212245299341391447497543589639683738
odděleních.14323250012155113169219243294349372417472493
Tento1948325001215094149182236
zdánlivě2207325001214399147202226249297346
neškodný25763250012155106145192246303358404
zákrok3003325001214393139173228275
může33013250012184138181231
někdy35553250012156106153208256
vést340339001214897137171
k5313390012147
zánětu598339001214393148198232287
měkkých9053390012183134181229280324379
částí1304339001214593132166189
kůže15143390012146102145194
(flegmóně),172933900121285582132189272327383433459478
osteomyelitidě2227339001215594128177233317362412436459492515571622
paty28693390012157106138188
nebo30773390012156106163219
bakteriemii.33173390012157105152188237270294344427451474494
Flegmóna340353001214971122179263319375424
kalkanea792353001214897121168218273324373
novorozenců11933530012156112159214247302344395451496551
je1773353001212475
vzácná1877353001214893144189245293
a21993530012148
neobvyklá22763530012156107163220268319367393441
infekce.2746353001212379108159206250300320
Autoři30953530012162116149204237261
prezentují3384353001215791141185235291324379403427
šestnáctidenního340367001214090129163219267311347370426477532587610668723
novorozence10813670012155111158212245299341391447492541
s16403670012139
rozvojem1698367001213287129179233257307391
flegmóny2107367001212956106163246301357403
měkkých25283670012183134181229279323378
částí2925367001214493132166189
pravého3132367001215790138185234290345
kotníku34953670012147101134189212261316
a3403810012148
paty4143810012157106139188
se629381001213990
zhojenou745381001214398153177227283338394
incizí,1165381001212378123146189213233
po14243810012157113
kapilárním1563381001214796153177200248280336359443
odběru20323810012155112169220252308
suché2366381001214094139194245
kapky2637381001214796153200250
(Guthrieho2913381001212991147180235267291341397452
testu).3391381001213383122156211236255
Původcem367238100121531073403950012148102159204253337
infekce697395001212378107157205248297
byl10143950012157104128
Streptococcus1162395001214776107152205236287329380423463515551
agalactiae17303950012152105157180232274306329380426
typu2175395001213178131183
III,23753950012124477192
který2485395001214783132165215
jsme2720395001212463146197
prokázali2937395001215790144191241284334357380
v33373950012148
odebrané34053950012155112162220253301356407
hemokultuře.3404090012156107192248296352376410465498549569
Včasná938409001215799149188244293
a12604090012149
cílená133740900121466995146203251
antibiotická16174090012149105138161219243299332356401448498
léčba2144409001212475121179228
vedla2401409001214999157181229
k26594090012148
úpravě27354090012156114147197244294
všech3057409001214989140186242
zánětlivých3328409001214394150201235259282331383427483
a3404230012148
klinických40942300121477295151174218265315359414
příznaků844423001215790113156212260306361
a12274230012148
zabránila1296423001214393149182231286309332380
rozvoji1698423001213287129180233257280
osteomyelitidy2000423001215594128177233316362411435458491514571618
kalkanea.2640423001214796119166215270321369390
Klíčová340439001246291118164222274327
slova:694439001244472130183236262
flegmóna984440001212956106164247303359407
kotníku,14194400012147101134190213262318339
novorozenec,17864400012156111159213246301343393449500546567
Guthrieho23814400012165121154210242266317373428
test,2838440001213382122156177
Streptococcus3044440001214776108153206237288331382425466518554
agalactiae36224400012153105158340454001212375117149172223269
sérotyp627454001213782114165196243295
III.9404540012124477110104540012121
Streptococcus340481001245186124174231267323367423468511568610
agalactiae9694810012455112168195251295332359415465
as1455481001245396
a15724810012452
cause1645481001244598156200254
of1919481001245892
soft20324810012443101136175
tissue2227481001243765109153211264
phlegmon25114810012460119147200260346404463
of2995481001245792
the3107481001243797150
ankle32774810012453112166195249
in340495001242786
a4474950012452
newborn5204950012458111187248306344403
secondary943495001244497143201260320373411466
to1429495001243795
the1544495001243797150
Guthrie17144950012468127165224263290343
test2077495001243790134171
Heel-prick3405130012165115165189220278310333377423
blood781513001215680134189246
sampling1044513001213988170226250272327382
in1444513001212378
newborns15395130012155105177234289322377415
is1971513001212462
a20505130012148
common2116513001214497180262317372
method25055130012183133166220275331
used2854513001215493143199
to3071513001213386
collect3174513001214598121144194239274
capillary3465513001214593149172195217265297347
blood340527001215781136192249
in611527001212379
neonatal7125270012155106161217265298347370
departments.11045270012156107164212245281364415470503543564
This16905270012150107130168
seemingly1880527001214090141225248303360383430
harmless23325270012156104136220244294334373
procedure2727527001215789144190239296351383433
can3182527001214593149
sometimes3353527001213994178229262285368419458
lead340541001212474122179
to545541001213387
inflammation659541001212378107134182265348396429452507562
of1248541001215584
the1358541001213389139
soft1524541001213994123160
tissues171054100121335695134189239278
of2015541001215584
the2125541001213489139
skin2291541001213986111166
(cellulitis),2483541001212970119143166221244267301324362387406
heel29155410012156106157181
osteomyelitis,3123541001215594128177233317362411435458492515553574
or3724541001215588
bacteremia.3405550012157106150186235268318401424472493
Calcaneal8585550012158106130175223278329377400
cellulitis1283555001214594118141195219242275298337
in1644555001212479
newborns17475550012156106179237293325381420
is2191555001212463
a22785550012148
rare2351555001213281113163
and25395550012148103160
unusual27235550012155110165204258307330
infection.3077555001212479108158204239262317373394
The34955550012150106157
authors36765550012148103340569001213388143176217
present578569001215790140180230286318
a9185690012148
16-day-old988569001215198132191239285316373397454
newborn14645690012155106179236292325381
who18675690012173129184
developed20735690012157107155204228283340391448
soft2543569001214095124160
tissue272556900121335795134189239
cellulitis2986569001214594118141196219242275298337
of3345569001215584
the3451569001213388138
right3611569001213357113168200
ankle3405830012148103150175226
and5855830012148103160
heel,7645830012156106157181202
with985583001217497130185
a11905830012148
healed12575830012156106154178228285
incision,1562583001212378123146185208263319339
following1921583001212984108131186259283338394
a23345830012148
capillary2402583001214593150174197220268300351
blood2772583001215781136192249
collection3040583001214599123146196242277300355411
(Guthrie3470583001212991147180235267291341
test).340597001213382121154181199
The5565970012150106156
causative729597001214593147185234266288336385
agent11315970012148104153208240
of1389597001215483
the1490597001213287137
infection1644597001212478107156202236259313369
was20305970012173121160
Streptococcus2207597001214980112161218250304349402447490544583
agalactiae28075970012148104151174222266301324371421
type3245597001213382139190
III,34535970012123477091
which35625970012173128151195250
was3406110012174122161
detected5226110012157107141190236271320377
in921611001212378
the1021611001213388138
infant‘s1181611001212378107156212244268305
blood1508611001215781136192249
culture.17786110012145100123156211244293314
Timely2113611001215074158208232280
and24146110012148103160
targeted2595611001213382115170221254303361
antibiotic29776110012148103136159215239294327350395
treatment3393611001213366115164196279330385418
led340625001212474131
to499625001213387
the614625001213388138
resolution780625001213383122177201256289312367423
of1231625001215584
all134262500121497295
inflammatory1465625001212378107134182265348396429483516566
and20596250012148103160
clinical224662500121456891147170214263286
symptoms2560625001214088172229262316399438
and30266250012148103160
prevented3214625001215790139187236292324373431
the3672625001213389139
development3406390012156107154203227283340423474530562
of923639001215584
calcaneal1028639001214594117162211266316364388
osteomyelitis.1437639001215594128177233317362412436459492515554575
Key3406550012462114166
words:5336550012477134173234278304
flegmon866656001212956107164248304360
of1255656001215585
the1368656001213389140
ankle,15376560012148104151176227247
newborn,18136560012156107181239295328385406
Guthrie22476560012165121155211243267318
test,2593656001213484124158179
Streptococcus2801656001214777108153207238289333384427468520556
agalactiae33826560012153105158181234276309331384429
serotype340670001213782114165196243295341
III.6996700012124477192
Úvod3407170014780142208279
Flegmóna480734001094463108158233282332374
a8697340010943
osteomyelitida926734001095085114158208283323367388408437457508550
paty1491734001095194123167
je1673734001092166
vzácná1754734001094383127167216258
infekce34074800109217197143185225269
u6337480010950
novorozenců,7077480010951101143192221271308354404445494513
která1244748001094275119149193
se1461748001093681
může15667480010976126164209
rozvinout18007480010929791161621843407620010951103154185
hematogenním552762001095198176221251301354401453504525603
šířením118276200109365891137189210288
nebo1497762001095198151203
přímou1727762001095383105183234285
inokulací340776001092169117159207227269308327
po6817760010951100
invazivním794776001092169110152190210252301321394
zákroku.1202776001093881122151199240289307
V15227760010950
současnosti1585776001093684132172214248296344378408427
se2140720001093682
na2247720001095195
novorozeneckých23667200010951101144194224273312357408454496538584624674
jednotkách3065720001092268120171221251293338379430
provádí3519720001095282132175219271292
odběr21407340010949100151196225
kapilární2385734001094286137157178221249299319
krve2724734001094273118162
z29067340010938
paty.2964734001095295124168182
Přestože3166734001094876120155185233271315
se3501734001093681
jedná3602734001092266117167209
pro2140748001095180129
novorozence2287748001095099141189218267304349398438482
o27877480010950
invazivní2855748001092170111155193214257307327
výkon,3200748001094489131179228246
neměl3465748001095095169214235
by3719748001095192
Guthrieho21407620010958107136185213233278327375
test2529762001093073108138
představovat2681762001095179123174208237280321369411453482
zvýšené3177762001093883127162206255300
riziko349176200109295087107148196
zánětu37017620010938822140776001094994123171
měkkých23247760010975119160202246285333
částí2671776001094082116146165
s28507760010935
rozvojem2899776001092977114158205226270343
osteomyelitidy,3256776001094983113156205279318362382402431450500542555
DECLARATIONS:4068314008648871301662142563043393604124625014570314008514
Declaration406832700874987120141179206244271291333375
of445732700874066
originality:45373270087406888130150192230251271298337356
The406833900853473109
manuscript418833900855891130168195227249266306329
is452833900851744
original45833390085386178117133172205222
and481633900853472112
has49393390085387299
not50503390085387699
been516133900853975110149
published532233900853977117134150177216251291
or406835000853862
submitted414535000852867108167184208234269310
elsewhere.44703500085355381117169209245269305320
Ethical406836300873764107127160198218
principles43003630087427090132165185228249287319
compliance:463336300873173134177197218256298330368387
The406837400853678116
authors420537400853475100142183208238
attest44643740085356087124153179
that466437400852465101126
their481137400852465103121146
study49783740085295595138173
was517237400855490119
approved531237400853577120145186221258301
by406838500854073
the41583850085236399
local42743850085175689124141
Ethical44323850085345898115147182199
Committee464838500854179139198215239265300337
and500238500853373113
is513238500851745
in519438500851656
compliance526738500853169129169187204239278311346
with40683960085537298140
human423639600854081143180221
studies44863960085285596139157195226
and474039600853577119
animal48883960085347695156193212
welfare512839600855391110133170196234
regulations53903960085236110414516420140684070085234080120148
of423540700853960
the43154070085236399
authors’44344070085347397136176200229244
institutions46984070085165684109126150189213231270310338
as505640700853462
well513840700855187104122
as527940700853462
with53614070085526993133
the55144070085236299
World406841800856099124142184
Medical427341800855795137155188224242
Association453541800854474104144178196231256273314355
Declaration491141800854785119136172196232257274315356
of528841800853961
Helsinki537041800854684102131149189224243
on406842900854082
Ethical418542900853561104123157195214
Principles44344290085386383125160179222242281311
for47804290085216389
Medical490442900855897141160194232251
Research519042900853978108147184210244287
ing551142900851759102
Human406844000854685145179219
Subjects430744000853474114132168201227256
adopted458344000853474114155179215256
by485844000854074
the49524400085236399
18th507144000853669514144100501437
WMA5198440008559116160
General537844000854582122158182217235
Assembly406845100854475105143204247266302
in439345100851758
Helsinki,447445100854785104134152193228248264
Finland,47614510085355394113149190232249
in503345100851758
June511545100852667109147
1964,528545100853771110150166
with54744510085537297139
subsequent406846200852867107136172213252288328352
amendments,443746200853493130169210269305345369398414
as486846200853462
well494846200855287105122
as508846200853362
with51674620085526993133
the53184620085236298
ICMJE543446200851759116143179
Recommendations406847300853977112153216278317359402439465483525568598
for46974730085226389
the481847300852466104
Conduct,495447300854283125168210245272290
Reporting,527547300853978121163189217236278321338
Editing,40684840085347491115132172212227
and430848400853373113
Publication443448400853776117134151183218242259298338
of478548400853859
Scholarly485748400853467106146163198221239273
Work514248400856097121155
in531048400851656
Medical537848400855693134151183218235
Journals,406849500852666105129169204221249265
updated435349500853980121155179215256
in462949500851656
December470549500854683116151211252289313
2018,503749500853673107140156
including52134950085165689106145186203243283
patient55164950085407540685060085234076116140
consent422250600853270110138174214238
where447550600855191127151187
appropriate.467750600853474115139178219243260295318354369
Conflict406852000874282124149171191223251
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interest44135200087196288126154192224251
and467852000873779122
financial48145200087244587125167200220258279
disclosures:51075200087416293126147188220261289327359378
None.406853100854686126162177
Funding/Support:406854500873777119162183225267291329371414457499526554574
Tento406855600853669111136177
článek42795560085335187129167203
vznikl451655600853569111129164184
v4734556008535
rámci480355600852460122156175
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SALVAGE,531555600853681116154197243281298
registrační406856700852460102120149173198234267308326
číslo:4418567008533507997138153
CZ.02.01.01/00/22_008/0004644,45965670085418310013817519122926427731535037240944847351154958762566570372976680584488392296210011017
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Cit.4068714008541588297
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Pediatr.429971400863975117136173198224238
praxi.455271400864067103139158176
2025;26(4):253-256474371400863775112150167205243264301321338377415452475510549587
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Mihál,474376600875980122160180199
CSc.495676600874281114134
Vladimir.Mihal@fnol.cz40687780085395792132149208225249262320338377412429482504544583601617649681