Pediatr. praxi. 2026;27(4):227-234 | DOI: 10.36290/ped.2026.038

Comprehensive management of the pediatric neuro-oncology patient

MUDr. Jana Táborská, Ph.D.^{1, 2}, doc. MUDr. Michal Zápotocký, Ph.D.^{2, 3}, doc. MUDr. Vladimír Beneš III., Ph.D.^{1, 2}

¹ Neurochirurgická klinika dětí a dospělých 2. lékařské fakulty a Fakultní nemocnice Motol a Homolka, Praha

² Centrum dětské neuroonkologie 2. lékařské fakulty a Fakultní nemocnice Motol a Homolka, Praha

³ Klinika dětské hematologie a onkologie 2. lékařské fakulty a Fakultní nemocnice Motol a Homolka, Praha

Among pediatric malignancies, central nervous system (CNS) tumors represent the leading cause of cancer-related mortality. The overall five-year survival rate for pediatric patients with brain tumors is around 80 %. However, survival outcomes vary significantly across specific diagnoses. The heterogeneity of these diagnoses, along with anatomical locations and other clinical variables, results in substantial variability in the available therapeutic modalities for each individual patient. The cornerstone of pediatric brain tumor management is a comprehensive, multidisciplinary asses­sment of the patient, carefully weighing the treatment options and their associated risks. Centralizing patients into specialized treatment centers allows for the optimal prevention of complications, facilitates interdisciplinary coordination, and ensures a systematic approach to both postoperative and long-term follow-up care.

Keywords: comprehensive management, neurooncology, brain tumors, pediatric neurosurgery.

Accepted: September 3, 2026; Published: September 17, 2026  Show citation