Pediatr. praxi. 2009;10(6):382-384

The neonatal withdrawal syndrome and its therapy

MUDr.Veronika Stará, MUDr.Petra Lesná, MUDr.Filip Fencl, Ph.D., doc.MUDr.Květa Bláhová, CSc.
Pediatrická klinika 2. LF UK a FN Motol, Praha

The authors describe neonatal withdrawal syndrome (NWS), its symptoms, therapy and potential complications for the foetus during

pregnancy as a consequence of drug-addicted mother. NWS occurs in newborns exposed to opioids, stimulans, canabinoids and other

drugs, the wide range of signs of NWS is an impact of withdrawal on both central and vegetative nervous systems, gastrointestinal system

and respiratory system. For the evaluation of symptoms and seriousness of NWS the Finnegan score is used worldwide; the Finnegan

score higher than 8 points is an indication to start substitutive therapy. A long-term therapy of NWS is necessary very often. There is an

evidence of better outcome for patients, whose mothers undergo substitutive therapy during the pregnancy.

Keywords: drugs in pregnancy, neonatal withdrawal syndrome, Finnegan score, substitutive therapy

Published: January 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Stará V, Lesná P, Fencl F, Bláhová K. The neonatal withdrawal syndrome and its therapy. Pediatr. praxi. 2009;10(6):382-384.
Download citation

References

  1. Vavřinková B, Binder T. Návykové látky v těhotenství. Zaostřeno na drogy 2007; 5(4): 1-12.
  2. Výroční zpráva ČR - 2007: Incidence, prevalence, zdravotní dopady a trendy léčených uživatelů drog. Hygienická stanice Hl. m. Prahy, Centrální pracoviště drogové epidemiologie, Praha 2008.
  3. Fišárková B, Tkaczyk J. Novorozenec drogově závislé matky - zásady postnatální péče. Neonatologické listy 2008; 14(2): 11-14.
  4. Bada HS, Das A, et al. Low birth weight and preterm births; etiologic fraction attributable to prenatal drug exposure. J Perinatol. 2006; 26: 11-14. Go to PubMed...
  5. Bishai R, Koren G. Maternal and obstetric effects of prenatal drug exposure. Clin Perinatol. 1999; 26(1): 75-106. Go to original source... Go to PubMed...
  6. Forrester MB, Merz RD. Risk of selected birth defects with prenatal illicit drug use, Hawaii, 1986-2002. J Toxicol Environ Health A. 2007; 70: 7-18. Go to original source... Go to PubMed...
  7. American Academy of Pediatrics Commitee on Drugs. Neonatal drug withdrawal. Pediatrics 1998; 101: 1079-1088. Go to original source...
  8. Kassima Z, Greenough A. Neonatal abstinence syndrome: Identification and management. Current Paediatrics 2006; 16: 172-175. Go to original source...
  9. Finnegan LP. Prenatal drug exposure. In: Clinical manual of substance abuse. Second ed. Philadelphia: Mosby. 1996: 257-271.
  10. Finnegan LP. Neonatal abstinence syndrome: assessment and pharmacolotherapy. In: Neonatal therapy: An update. New York, NY: Excerpta Medica; 1986: 122-146.
  11. Jansson LM, Choo R, et al. Methadone maintenance and breastfeeding in the neonatal period. Pediatrics 2008; 121: 106-114. Go to original source... Go to PubMed...
  12. Johnson K, Gerada C, Greenough A. Treatment of neonatal abstinence syndrome. Arch Dis Child Fetal Neonatal Ed. 2003; 88(1): F2-5. Go to original source... Go to PubMed...
  13. Oei J, Lui K. Management of the newborn infant affected by maternal opiates and other drugs of dependency. J Paediatr Child Health. 2007; 43(1-2): 9-18. Go to original source... Go to PubMed...
  14. Van Baar A, de Graaf BMT. Cognitive development and preschool-age of infants of drug - dependent mothers. Dev Med Child Neurol. 1994; 36: 1063-1075. Go to original source... Go to PubMed...
  15. Vance JC, Chant DC, Tudehope DI, et al. Infants born to narcotic dependent mothers: physical growth patterns in the first 12 months of life. J Paediatr Child Health 1997; 33(6): 504-508. Go to original source... Go to PubMed...




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.