Pediatr. praxi. 2010;11(2):118-120

Case of a thirteen-year-old patient with a history of complicated Lyme arthritis

MUDr.Peter Mikolášek1, MUDr.Lenka Krbková, CSc.1, MUDr.Jan Pavelka1, MUDr.Lukáš Homola1, doc.MUDr.Drahomíra Bartošová, CSc.1, MUDr.Šimon Ondruš2, MUDr.Jana Bednářová, Ph.D.3, prof.MUDr.Boris Habanec, DrSc.4
1 Klinika dětských infekčních nemocí LF MU a FN Brno
2 Klinika dětské chirurgie, ortopedie a traumatologie LF MU a FN Brno
3 Mikrobiologické oddělení FN Brno
4 II. patologicko-anatomický ústav LF MU a FN Brno

The diagnosis of Lyme borreliosis is beginning to emerge more often as a nosologic unit not only in explicit forms but also in difficult

to diagnose cases in daily routine of pediatricians and other specialists. Even after treatment lege artis the most immunogenic form

of Lyme borreliosis, Lyme arthritis, can cause chronic joint problems or potentiate developing of autoimmune disorders not only in

children. In the paper we introduce a case of a complicated Lyme gonitis that required surgical intervention.

Keywords: lyme borreliosis, autoimmunity, Borrelia burgdorferi, arthritis

Published: May 1, 2010  Show citation

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Mikolášek P, Krbková L, Pavelka J, Homola L, Bartošová D, Ondruš Š, et al.. Case of a thirteen-year-old patient with a history of complicated Lyme arthritis. Pediatr. praxi. 2010;11(2):118-120.
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References

  1. Wang G, Dam A, Schwartz I, et al. Molecular typing of Borrelia burgdorferi sensu lato: taxonomic, epidemiological, and clinical implications. Clin Microbiol Rev 1999? 4: 633-653. Go to original source... Go to PubMed...
  2. Steere A, Coburn J, Glickstein L. The emergency of Lyme disease. J Clin Investig 2004? 8: 1093-1101. Go to original source...
  3. Neubauerová V, Macela A, Hernychová L, et al. Proteomová analýza mikroorganismu Borrelia garinii. Voj Zdrav Listy 2008? 3: 107.
  4. Gross D, Steere A, Huber B. T helper 1 response is dominant and localized to the synovial fluid in patients with Lyme arthritis. J Immunol 1998? 160: 1022-1028. Go to original source...
  5. Steere A, Klitz W, Drouin E, et al. Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide. J Experiment Med 2006? 4: 961-969. Go to original source... Go to PubMed...




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