Pediatr. praxi. 2010;11(3):190-192

Panuveitis and aspergillus inflammation in pulmonary sequestration - exist some relevance?

doc.MUDr.Michal Hladík, Ph.D.¹, MUDr.Veronika Křivská¹, MUDr.Jana Čermáková¹, MUDr.Tomáš Pískovský¹, MUDr.Pavel Šmehlík², MUDr.Dalibor Cholevík², MUDr.Petr Mašek, CSc.², MUDr.Marcel Mitták, Ph.D.³

¹ Klinika dětského lékařství, Fakultní nemocnice Ostrava

² Oční klinika, Fakultní nemocnice Ostrava

³ Chirurgická klinika, Fakultní nemocnice Ostrava

The authors present a rare case report of 17-years-old girl. The problems started with panuveitis of the right eye treated with corticosteroids,

envolved with refractery progressive right bronchopneumonia despite of aggressive antibiotic therapy. The CT scan shows an

inflammatory destruction in right pulmonary lobe described like pulmonary gangrene, that required a surgical treatment. Perioperative

findings confirmed an intralobar pulmonary sequestration. Aspergillus fumigatus was by cultivation and as well as microscopically identified.

Although massive treatment with antibiotics, antimycotics and corticosteroids was administered, non-operative vitreous humour

opacification with amaurosis expanded. Because of progression of optical damage the enucleation of the right eyeball was necessary.

Within searching for possible dissemination of mycosis, 4 small focuses was found in brain by MRI.

These focuses were diminished after antimycotic treatment. The authors discuss potentiality if invasive aspergillosis with subsequent

panuveitis can occur in individuals with cavities caused by cystic lung diseases.

Keywords: lung (pulmonary) sequestration, panuveitis, Aspergillus fumigatus

Published: July 1, 2010  Show citation