Pediatr. praxi. 2011;12(4):261-264

Malignant melanoma in children

MUDr.Jan Čelakovský, prof.MUDr.Karel Pizinger, CSc.
Dermatovenerologická klinika FN Plzeň

The aim of this article is to review distinctive features of malignant melanoma in pediatric population. About 2–3 % of melanomas occur in

patients less than 20 years of age. Only 0.3 % of melanomas occur prior to puberty almost always arising in giant congenital melanocytic

nevi. In children, the risk factors include in particular giant congenital melanocytic nevi, familial dysplastic nevus syndrome, positive

family history, UV exposure, sunburn and immunodeficiency. Prompt pediatric and dermatological examination in every suspicious skin

lesion is essential. Authors also discuss some differences in comparison with adult melanoma.

Keywords: malignant melanoma, melanocytic nevi, metastases

Published: September 2, 2011  Show citation

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Čelakovský J, Pizinger K. Malignant melanoma in children. Pediatr. praxi. 2011;12(4):261-264.
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    References

    1. Pizinger K. Kožní pigmentové projevy. Praha: Grada: 15-91.
    2. Štork J, et al. Dermatovenerologie. Praha: Galén, 2008: 393-399.
    3. Braun-Falco O, Plewig G, Wolf H. Dermatologie und Venerologie. 5. Auflage Heidelberg: Springer Medizin Verlag, 2005: 1313-1323. Go to original source...
    4. Krajsová I. Melanom. Praha: Maxdorf, 2006; 216: 259-262.
    5. Livestro DP, Kaine EM, Michaelson JS, et al. Melanoma in the Young: Differences and Similarities with Adult Melanoma. Cancer, 2007? 110(3): 614-624. Go to original source... Go to PubMed...
    6. Paradela S, Fonseca E, Pita-Fernández S, et al. Prognostic Factors for Melanoma in Children and Adolescents. Cancer 2010? 15(116): 4334-4344. Go to original source... Go to PubMed...
    7. Fikrle T, Pizinger K. Maligní melanom. Onkologie 2010; 4(4): 225-228.
    8. Mills O, Messina JL. Pediatric Melanoma: A Review. Cancer Control 2009? 16(3): 225-233. Go to original source... Go to PubMed...
    9. Ceballos PI, Ruiz-Maldonado R, Mihm MC, Jr. Melanoma in Children. N. Engl. J. Med. 1995? 9(332): 656-662. Go to original source... Go to PubMed...
    10. Paradela S, Fonseca E, Pita S, et al. Spitzoid melanoma in children: clinicopathological study and application of immunohistochemistry as an adjunct diagnostic tool. J. Cutan. Pathol. 2009? 36: 740-752. Go to original source... Go to PubMed...
    11. Paller AS, Mancini AJ. Hurwitz Clinical Pediatric Dermatology. Third Edition: Elsevier Saunders, printed in China, 2006: 212-215.
    12. Pol-Rodriquez M, Lee S, Silvers DN, et al. Influence of Age on Survival in Childhood Spitzoid Melanomas. Cancer, 2007? 109(8): 1579-1583. Go to original source... Go to PubMed...
    13. Cerroni L, Barnhill R, Elder D, et al. Melanocytic tumors of uncertain malignant potential: results of a tutorial held at the XXIX Symposium of the International Society of Dermatopathology in Graz, October 2008. Am. J. Surg. Pathol. 2010? 34(3): 314-326. Go to original source... Go to PubMed...
    14. Lange JR, Palis BE, Chang DC, et al. Melanoma in Children and Teenagers: An Analysis of Patients from the National Cancer Data Base. J. Clin. Oncol. 2007? 25(11): 1363-1368. Go to original source... Go to PubMed...
    15. Aldrink JH, Selim AM, Diesen DL, et al. Pediatric melanoma: A single-institution experience of 150 patients. Journal of Pediatric Surgery 2009? 44(8): 1514-1521. Go to original source... Go to PubMed...
    16. Gill M, Cohen J, Renwick N, et al. Genetic Similarities between Spitz Nevus and Spitzoid Melanoma in Children. Cancer 2004? 101(11): 2636-2640. Go to original source... Go to PubMed...
    17. Hauschild A, Kaehler KC, Schaefer M, et al. Interdisziplinare Empfehlungen zum Nebenwirkungsmanagement einer Interferon-alfa-Therapie. JDDG 2008? 6: 829-838. Go to original source... Go to PubMed...
    18. Puzanov I, Flaherty KT. Targeted Molecular Therapy in Melanoma. Seminars in Cutaneous Medicine and Surgery. Elsevier Saunders, 2010: 196-200. Go to original source... Go to PubMed...
    19. Smalley KSM, Sondak VK. Melanoma - An Unlikely Poster Child for Personalized Cancer Therapy. N. Engl. J. Med. 2010? 26(363): 876-878. Go to original source... Go to PubMed...

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