Pediatr. praxi. 2013;14(1):45-47

Neuroborreliosis versus sclerosis multiplex

MUDr.Peter Mikolášek¹, MUDr.Lenka Krbková, CSc.¹, MUDr.Lukáš Homola¹, MUDr.Iva Čapovová¹, MUDr.Tomáš Habanec, Ph.D.¹, MUDr.Štefánia Rusnáková², MUDr.Marie Daňková², MUDr.Barbora Varadyová³, doc.MUDr.Jarmila Skotáková, CSc.⁴

¹ Klinika dětských infekčních nemocí LF MU a FN Brno

² Klinika dětské neurologie LF MU a FN Brno

³ Dětská oční klinika LF MU a FN Brno

⁴ Klinika dětské radiologie LF MU a FN Brno

Clinical symptoms in neuroborreliosis and multiple sclerosis can be similar at the begining of the disease. Basic laboratory values in both

diseases are quite non-specific, may be normal, or imitate a variety of other clinical entities. Therapeutic algorithm, severity of course

and particulary the possibility of permanent disability due to late diagnosis and treatment delay are quite different. Although there

are molecular mimicry hypotheses of lyme borreliosis as a potential trigger for multiple sclerosis (MS), there is not enough definitive

evidence for this opinion. The subject of this article is differential diagnosis, proper initiation and duration of therapy, including a case

report of a patient who fulfilled the clinical and laboratory criteria for both the MS and for neuroborreliosis.

Keywords: neuroborreliosis, multiple sclerosis, cerebrospinal fluid

Published: February 15, 2013  Show citation