Pediatr. praxi. 2016;17(3):173-176 | DOI: 10.36290/ped.2016.039

Lethargic infant: severe deficiency of vitamin B12

MUDr. Daniela Janečková1, MUDr. Martina Suková1, MUDr. Lucie ©rámková, Ph.D.1, MUDr. Elena Vodičková2, prof.MUDr. Jan Starý, DrSc.1
1 Klinika dětské hematologie a onkologie FN Motol, Praha
2 Oddělení klinické hematologie FN Motol, Praha

7-months-old infant was admitted to the hospital for progression of lethargy, pallor and hypotonia. Pancytopenia with normocytic anemia, elevation of lactatdehydrogenase were diagnosed. Aspiration of bone marrow was hypercellular, revealed hypersegmented neutrophils and megaloblastoid cells. Severe deficiency of vitamin B12 and sideropenia were confirmed. After parenteral vitamin B12 administration quick improvement of clinical status and hematopoiesis was observed.

Keywords: normocytic anemia, pancytopenia, lethargy, neuroanemic syndrome, vitamin B12 deficiency, sideropenia

Published: August 1, 2016  Show citation

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Janečková D, Suková M, ©rámková L, Vodičková E, Starý J. Lethargic infant: severe deficiency of vitamin B12. Pediatr. praxi. 2016;17(3):173-176. doi: 10.36290/ped.2016.039.
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    References

    1. Honzík T, et al. Nutriční defict vitaminu B12 u kojených dětí, Postgraduální medicína, 5/2008, dostupný z: http://zdravi.e15.cz/clanek/postgradualni-medicina/nutricni-deficit-vitaminu-b12-u-kojenych-deti-367850.
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    3. Honzik T, et al. European Journal of Paediatric Neurology, Volume 14, Issue 6, November 2010, 488-495, dostupný z: www.sciencedirect.com/science/article/pii/S1090379809002220. Go to original source... Go to PubMed...

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