Pediatr. praxi 2017; 18(5): 307-310 | DOI: 10.36290/ped.2017.060

Infantile hypertrophic pyloric stenosis in dizygotic twins

MUDr. Daniela Potyszová¹, prof. MUDr. Vladimír Mihál, CSc.¹, MUDr. Tomáš Malý, Ph.D.², MUDr. Kamila Michálková³

¹ Dětská klinika FN a LF UP v Olomouci

² I. chirurgická klinika LF UP a FN v Olomouci

³ Radiologická klinika LF UP a FN v Olomouci

Authors report a case of rarely hereditary occurrence of an infantile hypertrophic pyloric stenosis in dizygotic twins. First boy(twin B) was admitted to hospitalization in the fifth week after birth due to commencing dehydration caused by repetitive projectilevomiting, through the ultrasound pyloric stenosis was confirmed. After one week, the second boy (twin A) showed similarsymptoms with almost identical finding on the ultrasound. Both went through a procedure of pyloromyotomy without anypost-operative complications. Etiology of infantile hypertrophic pyloric stenosis is yet not clear, the influence is most probablymultifactorial. It includes genetic predisposition and environmental factors’ influence.It was detected that there is 200 times higher probability of appearance of infantile hypertrophic pyloric stenosis in monozygotictwins, 20 times higher in dizygotic twins and siblings (1). Among the external factors, there is a relation with mother’s smokingduring gravidity, administration of macrolide antibiotics to the children within the first two weeks of life or to the mothers duringlate stages of pregnancy or lactation (2).

Keywords: hypertrhophic pyloric stenosis, twins

Published: November 1, 2017  Show citation