Pediatr. praxi. 2021;22(5):312-314 | DOI: 10.36290/ped.2021.065

Acute postinfectious glomerulonephritis: one disease with many faces

doc. MUDr. Jakub Zieg, Ph.D.¹, doc. MUDr. Sylva Skálová, CSc.²

¹ Pediatrická klinika, 2. LF a FN v Motole, Praha

² Dětská klinika, FN Hradec Králové

Acute postinfectious glomerulonephritis is an acute glomerular inflammation that results from the preceding infection. Although multiple infectious agents can cause acute postinfectious glomerulonephritis, Streptococcus pyogenes remains the most common etiology of the disease. The clinical presentation varies from asymptomatic state to severe forms of nephritic syndrome or rapidly progressive glomerulonephritis. Decreased C3 complement level is typically associated with this type of glomerulonephritis. The therapy is mainly supportive, early diagnosis and management of hypertension is important. The prognosis is mostly favourable, however, long-term follow-up is needed in the majority of patients.

Keywords: acute postinfectious glomerulonephritis, post-streptococcal glomerulonephritis, nephritic syndrome, infective endocarditis, shunt nephritis.

Published: October 13, 2021  Show citation