Pediatr. praxi. 2022;23(6):409-410 | DOI: 10.36290/ped.2022.073
Sharp syndrome
- Klinika dermatovenerológie, Lekárska fakulta Univerzity Pavla Jozefa Šafárika a Univerzitná nemocnica Louisa Pasteura, Košice
Sharp syndrome (mixed connective tissue disease - MCTD) is a rare autoimmune disease combining the clinical symptoms of systemic lupus, systemic sclerosis, polymyositis and rheumatoid arthritis. Variability of clinical manifestations often delays the correct diagnosis. We demonstrate the case report of an 11-year-old patient diagnosed with Sharp syndrome. We point out the importance of immunofluorescence examination with evidence of antinuclear antibodies and their specification in the diagnosis of the disease. Due to the wide spectrum of clinical manifestations, interdisciplinary cooperation is essential.
Keywords: Sharp syndrome, mixed connective tissue disease.
Accepted: November 16, 2022; Published: November 22, 2022 Show citation
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