Pediatr. praxi. 2010;11(1):21-25 [Prakt. lékáren. 2009; 5(5): 219-222]

Optimal dosage of paracetamol for treating pain and fever

prof.MUDr.Miloslav Kršiak, DrSc.1, prof.MUDr.Jan Švihovec, DrSc.2, prof.Igor Zupanets, PhD.3, prof.MUDr.Milan Kriška, DrSc.4
1 Ústav farmakologie, 3. LF Univerzity Karlovy, Praha
2 Ústav farmakologie, 2. LF Univerzity Karlovy, Praha
3 Dpt. of Clinical Pharmacology, National University of Pharmacy, Kharkov, Ukraine
4 Ústav farmakológie, LF Univerzity Komenského, Bratislava

The generally stated and accepted single analgesic dose of paracetamol by mouth is 10–15 mg/kg. The SPCs and PILs of medications

containing 500 mg of paracetamol in adults recommend the dose of 1–2 tablets. Thus, in individuals with a body weight over 50 kg,

under dosage occurs with a dose of 500 mg, which may cause insufficient efficacy. The optimal dosage of paracetamol should be defined

based on the patient's body weight.

Keywords: acetaminophen, dosage, body weight, pain, fever

Published: March 1, 2010  Show citation

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Kršiak M, Švihovec J, Zupanets I, Kriška M. Optimal dosage of paracetamol for treating pain and fever. Pediatr. praxi. 2010;11(1):21-25.
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References

  1. Kobzová, et al. The 6th nationwide anthropological survey of children and adolescent in the Czech Republic in 2001. Centr Eur J Public Health 2004; 12: 126-130.
  2. Kunešová, et al. Životní styl a obezita: děti 13-17 let.
  3. http://www.rustovyhormon.cz/percentilove-rustovegrafy.




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