Pediatr. praxi. 2011;12(5):359-360

The role of prebiotics in prevention of allergy in children

MUDr.Jiří Bronský, Ph.D.
Pediatrická klinika UK 2. LF a FN Motol, Praha

Prebiotics are indigestible components of food that are not fermented in upper GI tract, but are fermented by colonic bacteria. Due to

this fact, they are able to support selectively growth of some profitable bacterial species (especially bifidobactaeria and lactobacilli)

and therefore positively influence health status of the organism. From artificially-produced prebiotics, the scGOS/lcFOS (9 : 1) combination

has been shown as the most effective. Current scientific data show that infant formulae supplemented with this prebiotic mixture

might possibly have positive effect on incidence of atopic dermatitis and other allergic diseases in infants with risk of atopy. The effect

of prebiotic-supplemented nutrition given in first six months of age might last later on in childhood. The prebiotic mixture is safe and

well tolerated by infants.

Keywords: prebiotic, allergy, infant nutrition, galactooligosaccharides, fructooligosaccharides

Published: November 1, 2011  Show citation

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Bronský J. The role of prebiotics in prevention of allergy in children. Pediatr. praxi. 2011;12(5):359-360.
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References

  1. Moro G, et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child 2006; 10: 418-419. Go to original source... Go to PubMed...
  2. Arslanoglu S, et al. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 2008; 138: 1091-1095. Go to original source... Go to PubMed...
  3. Arslanoglu S, et al. Neutral prebiotic oligosaccharide supplementation early in life and allergy associated symptoms later on: A five-year follow-up. Abstract, 44th ESPGHAN meeting, Sorrento, Italy, 2011: 127.
  4. Rijnierse, et al. Food-derived oligosaccharides exhibit pharmaceutical properties. Eur J Pharmacol. 2011 Jul 28. [Epub ahead of print]. Go to original source... Go to PubMed...




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