Pediatr. praxi. 2012;13(4):247-249

The new possibilities for extemporaneous cutaneous preparations in pediatrics

PharmDr.Zbyněk Sklenář, Ph.D., MBA1,2, Mgr.Kateřina Horáčková2, doc.MUDr.Ondřej Slanař, Ph.D.1
1 Farmakologický ústav, 1. lékařská fakulta, Univerzita Karlova v Praze
2 Lékárna Na Rohožníku, Praha

In recent years magistral preparation has been enriched with several new substances. This paper presents some possibilities of extemporaneous

preparation – semisolid preparations intended for the skin or mucosa application with local effect, suitable for pediatric

use. It introduces in detail three substances – dexpanthenol, sodium lactate solution and almond oil. The article presents examples of

suitable recipes for pediatric use: water-in-oil (w/o) cream with dexpanthenol and urea for infants, epithelizing ointment with vitamine E,

oil-in-water (o/w) cream with glycerine, nasal emulsion gel with vitamine E (Nasopanthil), ointment containing purified almond oil, zinc

oxide, dimeticone and vitamine E, cooling emolient cream and as suitable topical antimycotic an oil gel with nystatine is introduced.

Keywords: formulation in pharmacies, magistral (compounded) preparation, dexpanthenol, almond oil, sodium lactate solution

Published: August 24, 2012  Show citation

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Sklenář Z, Horáčková K, Slanař O. The new possibilities for extemporaneous cutaneous preparations in pediatrics. Pediatr. praxi. 2012;13(4):247-249.
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