Pediatr. praxi. 2013;14(3):192-194

When thrombocytopenia is not immune thrombocytopenic purpura

MUDr.Lucie Sulovská¹, MUDr.Ivana Stejskalová¹, MUDr.Hana Flögelová¹, RNDr.Ingrid Hrachovinová², doc.MUDr.Dagmar Pospíšilová, Ph.D.¹

¹ Dětská klinika, LF UP v Olomouci a FN Olomouc

Thrombotic thrombocytopenic purpura (syndrome Moschcowitz, TTP) is a very rare hematological disease in childhood and adolescent

age with incidence 1–4 cases/1 milion persons/year. It is characterized by reversible aggregation of thrombocytes in microcirculation,

whitch results in tissue and organ ischemia. Clinical symptoms are: skin and mucosal bleeding, anemic syndrome, neurological symptoms,

fever and renal involvement. In most cases, TTP starts with rapid onset of symptoms, whitch get worse dramatically in a few hours and

with inappropriate treatment can result in organ failure and death.

In our case report we present a patient, 17 years old girl, with atypical relapsing thrombotic thrombocytopenic purpura with severe

complications.

Keywords: thrombotic thrombocytopenic purpura, thrombocytopenia, hemolytic anemia, plasma exchange therapy

Published: July 15, 2013  Show citation