Pediatr. praxi 2018; 19(6): 322-324 | DOI: 10.36290/ped.2018.063

Is less known human granulocytic anaplasmosis not very significant at the same time?

RNDr. Helena Nejezchlebová, Ph.D., Bc. Renata Horáková, doc. RNDr. Alena Žákovská, Ph.D.

Ústav experimentální biologie, Přírodovědecká fakulta MU, Brno

We provide an overview of less known tick-borne zoonosis, human granulocytic anaplasmosis, with focus on mother and herfetus/child. In addition to the transfer of its bacterial causative agent (Anaplasma phagocytophilum) by ticks, other pathways ofinfection can not be excluded: blood transfusion, skin injury, inhalation of infected blood drops, transplacentar or through breastmilk. Coinfection with other tick-borne diseases may also occur, e. g. with borreliosis. Coinfection contributes to poor conditionof the patient an prolonged duration of clinical manifestations of the disease. A limited number of laboratory-confirmed cases ofanaplasmosis have been described in Europe, but A. phagocytophilum is a cosmopolitan organism, generally considered to be asignificant cause of infection in humans and animals. Increased population mobility and climate warming associated with a risein tick activity or spread of ticks to previously tick-free sites may also result in a higher risk of infection by tick-borne pathogensincluding A. phagocytophilum.

Keywords: human granulocytic anaplasmosis, Anaplasma phagocytophilum, Ixodes ricinus

Published: December 15, 2018  Show citation