Pediatr. praxi 2018; 19(6): 337-339 | DOI: 10.36290/ped.2018.066

Dextromethorphan – psychotropic drug in hands of children and adolescents

MUDr. Gabriela Rábová1, MUDr. Jiří Podlipný, Ph.D.1, PharmDr. Eliška Lacinová2, MUDr. Lucia Kovářová3, doc. MUDr. Jan Vevera, Ph.D.1
1 Psychiatrická klinika FN Plzeň a LF UK v Plzni
2 Klinika pracovního lékařství, Toxikologické informační středisko, 1. LF UK a VFN, Praha
3 Státní ústav pro kontrolu léčiv, Praha

Dextromethorphan (DXM) is a substance with increasing potential of abuse. Ordinary antitusic medicaments containing DXMused to be available without medical prescription in Czech Republic. Therefore it was easy to obtain and abuse. Since 15th August2018, the availability of monocomponent medicaments containing DXM in solid form changed due to a regulatory measure, whichconsists in the „only on medical prescription“ mode. It means that it cannot be sold over-the-counter anymore. We registered 5cases of DXM abuse in pediatric patients hospitalized in Department of Psychiatry, University Hospital in Pilsen during the first6 months of 2017. We present one case of a serious deliberate intoxication in a child 11 years old in this article. The intoxicationwas with a mixture of substances in this case and DXM in a toxic dose was the most important component. The increasing trendof DXM abuse in pediatric population is further discussed.

Keywords: dextromethorphan, psychotropic effect, abuse, pediatric population, intoxication

Published: December 15, 2018  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Rábová G, Podlipný J, Lacinová E, Kovářová L, Vevera J. Dextromethorphan – psychotropic drug in hands of children and adolescents. Pediatr. praxi. 2018;19(6):337-339. doi: 10.36290/ped.2018.066.
Download citation

References

  1. Wagner JB, Pine HS. Chronic cough in children. Pediatr Clin North Am. 2013; 60(4): 951-967. Go to original source... Go to PubMed...
  2. Boyer EW. Dextromethorphan abuse. Pediatr Emerg Care. 2004; 20(12): 858-863. Go to original source... Go to PubMed...
  3. Burns JM, Boyer EW. Antitussives and substance abuse. Subst Abuse Rehabil. 2013; 4: 75-82. Go to original source... Go to PubMed...
  4. http://www.ema.europa.eu/docs/en_GB/document_library/Minutes/2016/09/WC500213110.pdf
  5. http://www.hma.eu/fileadmin/dateien/Human_Medicines/CMD_h_/Agendas_and_Minutes/Minutes/CMDh_Minutes_July_2016.pdf
  6. http://www.sukl.cz/leciva/rozhodnuti-ek-dohoda-cmdh-k-vysledkum-psusa-2016
  7. Pender ES, Parks BR. Toxicity with dextromethorphan-containing preparations: a literature review and report of two additional cases. Pediatr Emerg Care. 1991; 7(3): 163-165. Go to original source... Go to PubMed...
  8. http://www.sukl.cz/stopex-na-suchy-kasel-30-mg-tablety-a-meddex-vicks-pastilky




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.