Pediatr. praxi. 2021;22(2):155-158

Cholin jako esenciální živina a jeho význam v těhotenství

MUDr. Simona Mlezivová, prof. MUDr. Pavel Calda, CSc.
Centrum fetální medicíny, Gynekologicko‑porodnická klinika 1. lékařské fakulty Univerzity Karlovy a Všeobecné fakultní nemocnice v Praze

Během těhotenství a kojení se podobně jako u dalších esenciálních živin zvyšuje poptávka po cholinu. Zároveň se předpokládá, že cholin je důležitý pro neurologický vývoj plodu a novorozence. Cholin je esenciální součástí buněčných membrán. Je to ve vodě rozpustná látka nezbytná pro metabolismus metylové skupiny, syntézu neurotransmiterů, strukturální integritu a signální funkce buněčných membrán. Jako prekurzor neurotransmiteru acetylcholinu může ovlivňovat kognitivní funkce a vývoj mozku. Přímý vztah mezi kognitivními funkcemi dítěte a hladinou cholinu u plodu v děloze byl prokázán ve studiích na zvířatech, ale není dostatečně prokázán u lidí.

Keywords: cholin, těhotenství, prekoncepce, esenciální živiny.

Published: April 29, 2021  Show citation

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Mlezivová S, Calda P. Cholin jako esenciální živina a jeho význam v těhotenství. Pediatr. praxi. 2021;22(2):155-158.
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