Pediatr. praxi. 2023;24(5):321-324 | DOI: 10.36290/ped.2023.081
SARS-CoV-2 infection and newborns
- 1 Neonatologické oddělení, FN Plzeň
- 2 Šiklův patologicko-anatomický ústav, FN Plzeň
This article discusses the risk of transmission of SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus) infection to the fetus in utero. Transplacental transmission of the virus is possible but is rare due to the special protective equipment of the placenta. In the authors' own cohort of parturients, the risk of fetal and neonatal infection was low. They examined histological changes in the placentas of the affected mothers and described a picture of placentitis caused by SARS-CoV-2 infection. The authors added an illustrative case report of a premature infant with congenital SARS-CoV-2 infection.In the discussion, the authors then describe the possibilities and details of SARS-CoV-2 transmission to the fetus and newborn, neonatal disease, and prognosis based on literature references.
Keywords: SARS-CoV-2 infection, pregnancy, vertical transmission, placentitis.
Accepted: October 9, 2023; Published: October 13, 2023 Show citation
References
- Beesley MA, Davidson JR, Panariello F, et al. COVID-19 and vertical transmission: assessing the expression of ACE2/TMPRSS2 in the human fetus and placenta to assess the risk of SARS-CoV-2 infection. BJOG. 2022;129(2):256-266.
Go to original source... 
Go to PubMed... - Blumberg DA, Underwood MA, Hedriana HL, et al. Vertical Transmission of SARS-CoV-2: What is the Optimal Definition? Am J Perinatol. 2020;37(8):769-772. Go to original source... Go to PubMed...
- Peng Z, Zhang J, Shi Y, et al. Research progresses in vertical transmission of SARS-CoV-2 among infants born to mothers with COVID-19. Future Virol. 2022 Jan:10.2217/fvl-2021-0213. Go to original source... Go to PubMed...
- Jamieson DJ, Rasmussen SA. An update on COVID-19 and pregnancy. Am J Obstet Gynecol. 2022;226(2):177-186. Go to original source... Go to PubMed...
- Joma M, Fovet CM, Seddiki N, et al. COVID-19 and Pregnancy: Vertical Transmission and Inflammation Impact on Newborns. Vaccines (Basel). 2021;9(4):391. Go to original source... Go to PubMed...
- Ryan L, Plötz FB, van den Hoogen A, et al. Neonates and COVID-19: state of the art: Neonatal Sepsis series. Pediatr Res. 2022;91(2):432-439. Go to original source... Go to PubMed...
- Cheema R, Partridge E, Kair LR, et al. Protecting Breastfeeding during the COVID-19 Pandemic. Am J Perinatol. 2023;40(3):260-266. Go to original source... Go to PubMed...
- WHO Frequently Asked Questions: Breastfeeding and COVID-19 For health care workers. J Hum Lact. 2020;36(3): 392-396. Go to original source... Go to PubMed...