Pediatr. praxi. 2024;25(4):218-222 | DOI: 10.36290/ped.2024.043

Interpretation of thyroid hormone results

MUDr. Jarmila Vojtková, PhD., MUDr. Alena Szökeová, MUDr. Terézia Kráľová, PhD., MUDr. Andrej Fiačan, MUDr. Anna Ďurdíková, PhD., prof. MUDr. Peter Bánovčin, CSc.
Klinika detí a dorastu, Univerzita Komenského Bratislava, Jesseniova lekárska fakulta a Univerzitná nemocnica, Martin, Slovensko

Dysfunction of thyroid gland is one of the frequent endocrinopathies in childhood, therefore thyroid hormones are investigated as part of the differential diagnosis of various symptoms. Positive autoantibodies indicate autoimmune thyroid disease, and its function is evaluated based on free thyroxin (fT4) and thyroid-stimulating hormone (TSH) results. Subclinical hypothyroidism is a debated finding, since slightly elevated TSH can occur after acute illness or can be related to other associated conditions (obesity, nephrotic syndrome, administration of certain drugs). The concentration of free triiodothyronine (fT3) depends mainly on deiodination by peripheral organs, therefore deviations from physiological values are quite frequent (e. g. with changes in weight, liver and kidney diseases). The article provides an overview of the most common laboratory findings and their correct interpretation with regard to wider contexts.

Keywords: thyroid gland, hormones, thyroid dysfunction, subclinical hypothyroidism.

Accepted: August 27, 2024; Published: September 5, 2024  Show citation

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Vojtková J, Szökeová A, Kráľová T, Fiačan A, Ďurdíková A, Bánovčin P. Interpretation of thyroid hormone results. Pediatr. praxi. 2024;25(4):218-222. doi: 10.36290/ped.2024.043.
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