Pediatr. praxi. 2010;11(6):368-372

Rational antibiotic therapy of acute otitis media in children view of clinical microbiologist

MUDr.Václava Adámková
Klinická mikrobiologie a ATB centrum, Ústav klinické biochemie a laboratorní diagnostiky,

Otitis media is one of the most common childhood infections. The most frequent causative agents are Streptococcus pneumoniae,

Haemophillus influenzae and Moraxella catarrhalis. Viruses play important role in the pathogenesis of otitis media. Treatment with

anti biotics is recommended for severe cases of otitis media and for children younger than 2 years. The drug of the first choice is

amoxicillin in the Czech Republic due to low prevalence of non-susceptible strains. Polysaccharide pneumococcal vaccine (PVC7) was

successful in reducing the incidence of otitis media caused by vaccine serotypes, but is observed the increase of episodes of acute

otitis media caused by nonvaccine serotypes in children who received PVC7.

Keywords: otitis media, etiology, antibiotics, PVC7

Published: December 9, 2010  Show citation

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Adámková V. Rational antibiotic therapy of acute otitis media in children view of clinical microbiologist. Pediatr. praxi. 2010;11(6):368-372.
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References

  1. Wintermeyer SM, Nahata MC. Chronic suppurative otitis media. Ann Pharmacother 1994; 28: 1089-1099. Go to original source... Go to PubMed...
  2. Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective, cohort study. J Infect Dis 1989; 160: 83-94. Go to original source... Go to PubMed...
  3. Rosenfeld R, Culpepper L, Doyle KJ, et al. Clinical practice guideline: Otitis media with effusion. Otolaryngol Head Neck Surg 2004; 130(Suppl 5): 95-118. Go to original source... Go to PubMed...
  4. Auinger P, Lanphear BP, Kalkwarf HJ, et al. Trends in otitis media among children in the United States. Pediatrics 2003; 112(3 Pt 1): 514-520. Go to original source... Go to PubMed...
  5. Prevention of hearing impairment from chronic otitis media. Report of WHO/CIBA Foundation Workshop. London, 19-21 November 1996. World Health Organization, 1998. WHO/PDH/98.4.
  6. Schwartz B, Giebink GS, Henderson GW, et al. Respiratory infections in day care. Pediatrics 1994; 94: 1018-1020. Go to original source... Go to PubMed...
  7. Bluestone CD, Klein JO. Otitis Media in Infants and Children. 4th ed. Hamilton, Ontario; BC ecker, 2007.
  8. Block SL, Hedrick J, Hararison CJ, et al. Community-wide vaccination with heptavalent pneumococcal conjugate vaccine significantly alters the microbiology of acute otitis media. Pediatr Infect Dis J. 2004; 23: 829-833. Go to original source... Go to PubMed...
  9. Casey JR, Pichichero ME. Changes in frequency and pathogens causing acute otitis media in 1995-2003. Pediatr Infect Dis J. 2004; 23: 824-828. Go to original source... Go to PubMed...
  10. Fireman B, Black SB, Shinefield HR, et al. Impact of the pneumococcal conjugate vaccine on otitis media. Pediatr Infect Dis J. 2003; 22: 10-16. Go to original source... Go to PubMed...
  11. Bodor FF, Marchant CD, Shurin PA, et al. Bacterial etiology of conjunctivitis-otitis media syndrome. Pediatrics 1985; 76: 26-28. Go to PubMed...
  12. Hartnick CJ, Shott S, Willging JP, et al. Methicillin-resistant Staphylococcus aureus otorrhea after tympanostomy tubeplacement. An emerging concern. Arch Otolaryngol Head Neck Surg. 2000; 126: 1440-1443. Go to original source... Go to PubMed...
  13. Segal N, Givon-Lavi N, Leibovitz E, et al. Acute otitis media caused by Streptococcus pyogenes in children. Clini Infect Dis. 2005; 41: 35-41. Go to original source... Go to PubMed...
  14. Klein JO, Teele DW. Isolation of viruses and mycoplasma from middle ear effusions. A review. An Otol Rhinol Laryngol. 1976; 85: 140-144. Go to original source... Go to PubMed...
  15. Tipple MA, Beem MO, Saxon EM. Clinical characteristics of the afebrile pneumonia associated with Chlamydia trachomatis infection in infants less than 6 months of age. Pediatrics 1979; 63: 192-197. Go to original source... Go to PubMed...
  16. Lowry PW, Jarwis WR, Oberle AD, et al. Mycobacterium chelonae causing otitis media in an ear-nose-and throat practice. N Engl J Med 1988; 391: 978-982. Go to original source... Go to PubMed...
  17. Monobe H, Ishibashi T, Nomura Y, et al. Role of respiratory viruses in children with acute otitis media. International Journal of Pediatric Otorhinolaryngology 2003; 67: 801-806. Go to original source... Go to PubMed...
  18. Žemličková H, Urbášková P, Adámková V, et al. Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus isolated from the nasopharynx of healthy children atteding day-care centres in the Czech Republic. Epidemiol. Infect. 2006; 134: 1179-1187. Go to original source... Go to PubMed...
  19. Bébrová E, Jindrák V, Kolář M, et al. Doporučený postup pro léčbu komunitních respiračních infekcí v primární péči. Praktický lékař 2003; 83: 502-515.
  20. Eskola J, Kilpi T, Palmu A, et al. Efficacy of a pneumococcal conjugate vaccine agains acute otitis media. N Engl J Med. 2001; 344: 403-409. Go to original source... Go to PubMed...




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