Pediatr. praxi. 2024;25(1):53-57 | DOI: 10.36290/ped.2024.010

Staphylococcal pyomyositis of the thigh muscle during induction therapy of acute lymphoblastic leukemia

prof. MUDr. Vladimír Mihál, CSc.^{1, 2}, MUDr. Barbora Ludíková, Ph.D.², MUDr. Zbyněk Novák², MUDr. Bohumil Zálešák, Ph.D.³, MUDr. Lenka Bakaj-Brožková, Ph.D.⁴

¹ Ústav molekulární a translační medicíny FN a LF UP v Olomouci

² Dětská klinika LF UP a FN v Olomouci

³ Oddělení plastické chirurgie LF UP a FN v Olomouci

⁴ Radiologický ústav, LF UP a FN v Olomouci

Primary pyomyositis is a purulent infection of the skeletal muscle often with abscess formation, which arises from a haematogenous infection. Primary infections usually have a subacute onset and most commonly affect one muscle group of the lower limb or the muscles of the hip and pelvis. We present a 16-year-old type I diabetic with with newly diagnosed acute lymphoblastic leukemia. Aggressive induction chemotherapy was complicated by febrile neutropenia on day 6. The patient reported right thigh adductor pain on walking, and we observed phlegmonous skin changes resembling a subcutaneous hematoma. We summarize the diagnostic and therapeutic procedures that led to a definitive diagnosis and therapeutic success.

Keywords: pyomyositis, muscle abscess, Staphylococcus aureus, adolescent, acute lymphoblastic leukemia, diabetes mellitus.

Accepted: February 12, 2024; Published: February 19, 2024  Show citation