Pediatr. praxi. 2025;26(1):62-66 | DOI: 10.36290/ped.2025.013

Clinical and imaging characteristics of midaortic syndrome

prof. MUDr. Vladimír Mihál, CSc.^{1, 2}, MUDr. Hana Flögelová, Ph.D.², MUDr. Lenka Bakaj-Brožková, Ph.D.³, MUDr. Kamila Michálková²

¹ Ústav molekulární a translační medicíny LF UP a FN v Olomouci

² Dětská klinika LF UP a FN v Olomouci

³ Radiologická klinika LF UP a FN v Olomouci

Middle aortic syndrome (MAS) is caused by stenosis of the thoracic and/or abdominal aorta, often accompanied by concomitant stenosis of the renal or visceral arteries. Although MAS is rare (0.5-2%), it is a serious cause of hypertension in children and adolescents with high morbidity. It is thought to arise from failure of fusion of the two dorsal aortas during embryonic development, and a high percentage of cases are idiopathic. Clinically, it presents with symptomatic or asymptomatic arterial hypertension. The method of choice today is angiography, non-invasive MR angiography and CT angiography have similar diagnostic accuracy. Ultrasonography is the primary screening technique. Treatment consists of a combination of various antihypertensive drugs. Surgical treatment may be curative. Our aim was to present the clinical picture, diagnosis and treatment of two new cases with MAS.

Keywords: hypertension, middle aortic syndrome, midaortic syndrom (MAS), renal artery stenosis, children.

Accepted: March 6, 2025; Published: March 19, 2025  Show citation