Pediatr. pro Praxi, 2006; 1

New paediatric indications for growth hormone therapy in Czech republic

doc. MUDr. Jiřina Zapletalová Ph.D¹, prof. MUDr. Jan Lebl CSc², MUDr. Jana Černá³, MUDr. Marcela Dvořáková⁴, MUDr. Vlasta Janštová³, MUDr. Božena Kalvachová CSc⁴, MUDr. Jarmila Klabochová⁵, MUDr. Stanislava Koloušková CSc⁶, prof. MUDr. Lidka Lisá DrSc⁶, MUDr. Olga Magnová⁷, MUDr. David Neumann⁸, MUDr. Eva Nováková⁹, MUDr. Dana Novotná¹⁰, MUDr. Renata Pomahačová¹¹, MUDr. Štěpánka Průhová Ph.D², MUDr. Jaroslav Škvor CSc¹², MUDr. Štěpánka Šnajderová CSc⁶, MUDr. Zdeněk Šumník Ph.D⁶

¹ Dětská klinika LF UP a FN Olomouc

² Klinika dětí a dorostu, UK 3. LF a FNKV, Praha

³ Dětská klinika FN, Ostrava

⁴ Endokrinologický ústav, Praha

⁵ Nemocnice u sv. Jiří, Plzeň

⁶ Pediatrická klinika 2. LF UK a FN Motol, Praha

⁷ Dětská klinika LF MU a FN, Brno

⁸ Oddělení dětské chirurgie a traumatologie FN a LF UK Hradec Králové

⁹ Dětská klinika FN, České Budějovice

II. dětská klinika LF MU a FN Brno;10

Dětská klinika FN a LF UK v Plzni;11

Dětská klinika, IPVZ, Ústí nad Labem;12

The current paediatric indications for growth hormone therapy in the Czech Republic include (growth hormone deficiency since 70thies years of 20ies century), Turner syndrome (since 1992), growth failure in subjects with chronic renal insufficiency (since 1995), Prader-Willi syndrome (since 2001) and postnatal growth failure following the intrauterine growth retardation (since 2003). As for January 1st, 2006, 922 children have been treated in 13 centres. Of these, growth hormone deficiency was proved in 537, Turner syndrome in 159 girls, chronic renal insufficiency in 28 children, Prader-Willi syndrome in 35 and postnatal growth failure following the intrauterine growth retardation in 163.

Keywords: growth hormone therapy, new indications, growth hormone deficiency, Turner syndrome, chronic renal insufficiency, Prader-Willi syndrome, intrauterine growth retardation

Published: January 1, 2006  Show citation