Pediatr. praxi. 2010;11(3):169-171

Renal involvement in Henoch - Schönlein purpura

MUDr.Jakub Zieg1, MUDr.Sylva Skálová, Ph.D.2
1 Pediatrická klinika 2. LF UK a FN Motol, Praha
2 Dětská klinika LF UK a FN Hradec Králové

Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood with skin, joint, gastrointestinal and renal symptoms.

Although most features are self-limiting, renal involvement can be permanent and is a major factor of long-term prognosis. Currently

there are no effective measures to prevent the onset of HSP nephritis, and similarly no commonly accepted therapeutic guidelines exist.

Early recognition of renal involvement together with long term follow-up are essential for patient prognosis.

Keywords: Henoch-Schönlein purpura, nephritis, treatment

Published: July 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Zieg J, Skálová S. Renal involvement in Henoch - Schönlein purpura. Pediatr. praxi. 2010;11(3):169-171.
Download citation

References

  1. Bogdanović R. Henoch-Schönlein purpura nephritis in children: risk factors, prevention and treatment. Acta Pediatr 2009; 98(12): 1882-1889. Go to original source... Go to PubMed...
  2. Rook A. William Heberden's Cases of Anaphylactoid Purpura. Arch Dis Child 1958 33(169): 271. Go to original source... Go to PubMed...
  3. Henoch EH. Über ein eigenthe Form von Purpura. Berl Klin Wochenschr 1974; 11: 641-643.
  4. Lau KK, Suzuki H, Novak J, Wyatt RJ. Pathogenesis of Henoch-Schönlein purpura nephritis. Pediatr Nephrol 2010; 25(1): 19-26. Go to original source... Go to PubMed...
  5. Tesař V, Schück O, a kol. Klinická nefrologie, Grada Publishing, Praha 2006: 224-225.
  6. Kaku Y, Nohara K, Honda S. Renal involvement in HenochSchonlein purpura: a multivariate analysis of prognostic factors. Kidney Int 1998; 53(6): 1755-1759. Go to original source... Go to PubMed...
  7. Rigante D, Candelli M, Federico G, et al. Predictive factors of renal involvement or relapsing disease in children with HenochSchönlein purpura. Rheumatol Int 2005; 25(1): 45-48. Go to original source... Go to PubMed...
  8. Tarshish P, Bernstein J, Edelmann CM. Henoch-Schönlein purpura nephritis: course of disease and efficacy of cyclophosphamide. Pediatr Nephrol 2004; 19(1): 51-56. Go to original source... Go to PubMed...
  9. Coppo R, Mazzucco G, Cagnoli L, et al. Long-term prognosis of Henoch-Schönlein nephritis in adults and children. Italian Group of Renal Immunopathology Collaborative Study on Henoch-Schönlein purpura. Nephrol Dial Transplant 1997; 12(11): 2277-2283. Go to original source... Go to PubMed...
  10. Butani L, Morgenstern BZ. Long-term outcome in children after Henoch-Schönlein purpura nephritis. Clin Pediatr 2007(6); 46: 505-511. Go to original source... Go to PubMed...
  11. Soylemezoglu O, Ozkaya O, Ozen S, et al. Turkish Pediatric Vasculitis Study Group: Henoch-Schönlein Nephritis: A Nationwide Study. Nephron Clin Pract 2009; 112(3): c199-204. Go to original source... Go to PubMed...
  12. ChartapisakW, Opastirakul S, Willis NS, et al. Prevention and treatment of renal disease in Henoch - Schönlein Purpura: a systematic review. Arch Dis Child 2009; 94(2): 132-137. Go to original source... Go to PubMed...
  13. Inoue CN, Chiba Y, Morimoto T, et al. Tonsillectomy in the treatment of pediatric Henoch-Schönlein nephritis. Clin Nephrol 2007; 67(5): 298-305. Go to original source... Go to PubMed...
  14. Dixit MP, Dixit NM, Scott K. Managing Henoch-Schönlein purpura in children with fish oil and ACE inhibitor therapy. Nephrology (Carlton) 2004; 9(6): 381-386. Go to original source... Go to PubMed...
  15. Zaffanello M, Fanos V. Treatment based literature of Henoch-Schönlein purpura nephritis in childhood. Pediatr Nephrol 2009; 24(10): 1901-1911. Go to original source... Go to PubMed...
  16. Niaudet P, Habib R. Methylprednisolone pulse therapy in the treatment of severe forms of Schönlein-Henoch purpura nephritis. Pediatr Nephrol 1998; 12(3): 238-243. Go to original source... Go to PubMed...
  17. Shin JI, Park JM, Shin YH, et al. Can azathioprine and steroids alter the progression of severe Henoch-Schönlein nephritis in children? Pediatr Nephrol. 2005; 20(8): 1087-1092. Go to original source... Go to PubMed...
  18. Shin JI, Park JM, Lee JS, et al. Successful use of cyclosporin A in severe Schönlein-Henoch nephritis resistant to both methylprednisolone pulse and azathioprin. Clin Rheumatol 2006; 25(5): 759-760. Go to original source... Go to PubMed...
  19. Shenoy M, Ognjanovic MV, Coulthard MG. Treating severe Henoch-Schönlein and IgA nephritis with plasmapheresis alone. Pediatr Nephrol. 2007; 22(8): 1167-1171. Go to original source... Go to PubMed...




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.