Pediatr. praxi. 2011;12(3):204-206

Treatment of pain in a patient suffering from metachromatic leukodystrophy

MUDr.Jarmila Pavlíková1, MUDr.Ludmila Bártlová2
1 Ambulance léčby bolesti ARO, Masarykův onkologický ústav, Brno
2 Klinika dětské neurologie FN Brno

Metachromatic leukodystrophy is a rare disease caused by an inherited disorder of myelin metabolism. Motor decline preceding cognitive

and behavioral symptoms is typical for a late-infantile form of disease. A three-year old girl diagnosed with metachromatic

leukodystrophy was suffering from painful paresis of her limbs. A sufficient pain relief was obtained using transdermal buprenorphine

and clonazepam.

Keywords: metachromatic leukodystrophy, pain, transdermal buprenorphine

Published: July 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Pavlíková J, Bártlová L. Treatment of pain in a patient suffering from metachromatic leukodystrophy. Pediatr. praxi. 2011;12(3):204-206.
Download citation

References

  1. Doležal T, Hakl M, Kozák J. Metodické pokyny pro farmakoterapii bolesti. Farmakoterapie 2010; 2: 171-176.
  2. McCormack K. Signal transduction in neuropathic pain, with special emphasis on the analgesic role of opioids - part II: Moving basic science towards a new pharmacotherapy. Pain Reviews 1999; 6: 99-131. Go to original source...
  3. Opavský J. Vyšetřování osob s algickými syndromy a hodnocení bolesti. Bolest, Tigis Praha 2006: 172-179.
  4. Ševčík P, Adam Z. Transdermální buprenorfin. Remedia 2006; 16: 514-521. Go to original source...
  5. Terri Voepel-Lewis A. Comparison of the Clinical Utility of Pain Assessment Tools for Children with Cognitive Impairment. Pediatric Anesthesiology 2008; 106(1): 72-78. Go to original source... Go to PubMed...




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.