Pediatr. praxi. 2011;12(5):361-362
Bacillus clausii - a probiotic resistant to antibiotics
- 1 Klinika dětského a dorostového lékařství 1. LF UK a VFN, Praha
- 2 Ústavy farmakologie 2. a 3. LF UK, Praha
- 3 Infekční klinika 2. lékařské fakulty UK a FN Na Bulovce, Praha
- 4 Edukafarm, Praha
Intestinal dysmicrobia (which could manifest itself as diarrhea) represents a frequent undesirable effect of antibiotic therapy. In the
management of complications associated with antibiotic treatment application of probiotics is recommended. Resistance to antibiotics
represents a significant precondition of effectiveness of a probiotic. Ofcourse, mere documentation of resistance to antibiotics is not
sufficient in terms of safety profile of a probiotic strain. It should also prove that the resistance is not tranferable to other microorganisms.
Spore-forming Bacillus clausii show high resistance to antibiotics that is not tranferable to other microorganisms, thus meeting the
standard demands on efficiency, but also on safety of therapy.
Keywords: probiotics, Bacillus clausii, diarrhea associated with antibiotic therapy, postantibiotic dysmicrobia, resistence to antibiotics
Published: November 1, 2011 Show citation
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