Pediatr. praxi. 2014;15(2):95-96
Erythema nodosum is considered to be a nonspecific immune response to an antigenic stimulus, most frequently an infectious one. The
authors present two case reports of 9-year-old classmates in whom an eruption of erythema nodosum was associated with a previously
undescribed combined infection with two pathogens: Chlamydia trachomatis and Salmonella enteritidis. The epidemiological association
of both the cases and a nearly identical clinical presentation, course and response to treatment were conspicuous. After reviewing
the literature, the authors discuss the potential effect of the infective agents themselves on the occurrence of erythema nodosum and
recommend more detailed paediatric and microbiological studies on this phenomenon.
association.
Published: April 20, 2014 Show citation