Pediatr. praxi. 2015;16(5):300-304

Hereditary cancer predisposition syndromes in childhood - the role of primary care pediatricians

MUDr.Viera Bajčiová, CSc.
Klinika dětské onkologie LF MU a FN Brno

Broad spektrum of hereditary cancer predisposition syndromes affecting pediatric population. Early genetic testing and diagnosis may

assist in patient dispensarisation and management. Earlier diagnosis of the cancer and improve prognosis and overall survival. A general

pediatrician is usually the first person to suspect some dyspmorhology and possible genetic syndrome.

Keywords: hereditary cancer predisposition syndromes, dysmorphology, pediatric cancer, genetic testing

Published: December 1, 2015  Show citation

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Bajčiová V. Hereditary cancer predisposition syndromes in childhood - the role of primary care pediatricians. Pediatr. praxi. 2015;16(5):300-304.
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    References

    1. Schiffman JD, Keller JI, Jundy E, et al. Update on pediatric cancer predisposition syndromes. Pediatr Blood Cancer 2013; 60: 1247-1252. Go to original source... Go to PubMed...
    2. American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility. J Clin Oncol 2003; 21(12): 2397-2406.
    3. Bjorge T, Cnattingius S, Lie RT, et al. Cancer risk in children with birth defects and their families: a population based cohort study of 5.2 million children from Norway and Sweden. Cancor Epidemiol Biomarkers 2008; 17(3): 500-506. Go to original source... Go to PubMed...
    4. Testa JR, Malkin D, Schiffman JD: Connecting molecular pathways to hereditary cancer risk syndromes. ASCO Educ Book 2013: 81-90. Go to original source...
    5. Foretová L. Hereditární malignity si zaslouží víc pozornosti než dosud: Kongresová review XXXIX. Brněnské onkologické dny 2015: 9-11.
    6. Závodná K, Milly M, Vavrová L, et al. Dědičné nádorové syndromy. Onkológia 2015; 10(2): 84-89.
    7. Škvor J, Průhová Š. Základy klinické genetiky pro klinickou praxi. Genetika v primární péči: 5-6. Mladá fronta 2014, Genetika v primární péči, ISBN 978-80-204-3413-5.
    8. Papakasama S, Tomlinson GE: Genetic predisposition and screening in pediatric cancer. Pediatr Clin North Am 2002; 49(6): 1393-413. Go to original source... Go to PubMed...
    9. Rao A, Rothman J, Nichols KE. Genetic testing and tumor surveillance for children with cancer predisposition syndromes. Curr Opin Pediatr 2008; 20(1): 1-7. Go to original source... Go to PubMed...
    10. Foretová L, Petráková K. Dispenzarizace dědičných nádorových syndromů. Klinická onkologie 2009; 22: supplementum: 6-77.
    11. Ilenčíková D, Amidová O, Konečný M et al: Genetická konzultácia jako súčasť genetického vyšetrenia. Onkológia 2015; 10(2): 74-76.
    12. Teplick A. Screening in cancer predisposition syndromes: guidelines for the general pediatricians. Eur J Pediatr 2011; 170(3): 285-204. Go to original source... Go to PubMed...
    13. Foretová L, Macháčková E, Gaillyová R, et al. Hereditární nádorová onemocnění, kapitola 5, str 116-155 v monografii Foretová L, Svoboda M, Slabý O: Molekulární genetika v onkologii, Mladá fronta 2014, ISBN 978-80-204-3236-0.
    14. Field M, Shanley S, Kirk J. Inhereted cancer susceptibility syndromes in paediatric practice. J Pediatr Child Health 2007; 4(4): 219-229. Go to original source... Go to PubMed...
    15. Kleibl Z, Novotný J. Hereditární nádorové syndromy. Vydavatelství Triton Praha, 2003.

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