Pediatr. praxi 2019; 20(4): 270-274

Functional digestive disorders, phytotherapy by preparation STW 5 (Iberogast®)

MUDr. Vít Navrátil
II. interní klinika – gastroenterologická a geriatrická, LF UP a FN Olomouc

Dyspepsia is one of the most common cause of visiting a pharmacy or a physician. It is a heterogenous group of unpleasant symptoms concerning the digestive tract, abdomen, intake of food and bowel movement. Subject of the first part of the article is a brief review of digestive disorders, especially functional disorders, and a brief classification of them. Moreover it contains a summary of treatment possibilities. STW 5 (Iberogast®) is a fixed herbal combination product, available as a over-the-counter medicine. It is an effective, safe and well tolerated medicine. The second part of the article concerns with composition and data summary about effectivity and safety of STW 5 (Iberogast®).

Keywords: dyspepsia, self‑medication,STW 5 (Iberogast®), clinical studies

Published: September 1, 2019  Show citation

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Navrátil V. Functional digestive disorders, phytotherapy by preparation STW 5 (Iberogast®). Pediatr. praxi. 2019;20(4):270-274.
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    References

    1. Over-the-Counter Medications: Use in General and Special Populations, Therapeutic Errors, Misuse, Storage and Disposal [online]. 2011. American College of Preventive Medicine [cit. 2019-06-111]. Dostupný na WWW: < https://c.ymcdn.com/sites/www.acpm.org/resource/resmgr/timetools-files/otcmedstimetool.pdf >
    2. Ehrmann J. Funkční dyspepsie. Medicína pro praxi 2013; 10(2): 50-53.
    3. Rejchrt S, et al. Prevalence a sociodemografická charakteristika dyspepsie v České republice. Hradec Králové: Nucleus 2005.
    4. Schmulson M. J., Drossman D. A. What Is New in Rome IV. J Neurogastroenterol Motil. 2017; 23(2): 151-163. Go to original source... Go to PubMed...
    5. Drossman D. A. Functional gastrointestinal disorders: history, pathophysiology, clinical features and Rome IV. Gastroenterology 2016; 150: 1262-1279. Go to original source... Go to PubMed...
    6. Kotolová H. Nezávažné trávicí potíže a možnosti samoléčení. Prakt. lékáren. 2019; 15(1): 46-53. Go to original source...
    7. Tan VP. The low-FODMAP diet in the management of functional dyspepsia in East and Southeast Asia. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1: 46-52. Go to original source... Go to PubMed...
    8. Werlang ME., Palmer, WC., Lacy BE. (2019). Irritable Bowel Syndrome and Dietary Interventions. Gastroenterology & hepatology, 15(1), 16-26. Go to PubMed...
    9. Leiman DA, Riff BP, Morgan S, et al. Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis. Dis Esophagus. 2017; 30(5): 1-9. Go to original source... Go to PubMed...
    10. Falzon CC, Balabanova A. Phytotherapy: An Introduction to Herbal Medicine. Prim Care. 2017 Jun; 44(2): 217-227. Go to original source... Go to PubMed...
    11. Rösch W, Liebregts T, Gundermann KJ, et al. Phytotherapy for functional dyspepsia: A review of the clinical evidence for the herbal preparation STW 5. Phytomedicine 2006; 13: 114-121. Go to original source... Go to PubMed...
    12. Kroll U, Cordes C. Pharmaceutical prerequisites for a multi-target therapy. Phytomedicine 2006; 13: 12-19. Go to original source... Go to PubMed...
    13. Ammon HPT, Kelber O, Okpanyi SN. Spasmolytic and tonic effect of Iberogasts (STW 5) in intestinal smooth muscle. Phytomedicine 2006; 13: 67-74. Go to original source... Go to PubMed...
    14. Bonaterra GA, et al. Mechanisms of the anti-proliferative and anti-inflammatory effects of the herbal fixed combination STW 5 (Iberogast(R)) on colon adenocarcinoma (HT29) cell in vitro. Phytomedicine 20 (2013); 691-698. Go to original source... Go to PubMed...
    15. S. Michael, et al. Inhibition of inflammation-induced alterations in rat small intestine by the herbal preparations STW 5 and STW 6. Phytomedicine 16 (2009); 161-171. Go to original source... Go to PubMed...
    16. Von Arnim U, Peitz U, Vinson B. STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol. 2007; 102: 1268-1275. Go to original source... Go to PubMed...
    17. Braden B, Caspary W, Börner N. Clinical effects of STW 5 (Iberogast) are not based on acceleration of gastric emptying in patients with functional dyspepsia and gastroparesis. Neurogastroenterol Motil., 2009; 21(6): 632-638. Go to original source... Go to PubMed...
    18. Rösch W, Vinson B, Sassin I. A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepsia. Z Gastroenterol. 2002; 40(6): 401-408. Go to original source... Go to PubMed...
    19. Sassin I, Buchert D. Efficacy and tolerability of the herbal preparation Iberogast(R) in the therapy of functional dyspepsia. Phytomedicine. 2000; 7: 91-92. Go to PubMed...
    20. Klein-Galczinsky C, Sassin I. Anwendungsbeobachtung zur Wirksamkeit und Verträglichkeit von Iberogast(R) in der Therapie des Colon irritabile. Phytotherapie an der Schwelle zum neuen Jahrtausend 1999; 125 (Abstract P25).
    21. Ottillinger B., Storr M., Malfertheiner P., Allescher H. D. STW 5 (Iberogast(R))--a safe and effective standard in the treatment of functional gastrointestinal disorders. Wien Med Wochenschr. 2013; 163(3-4): 65-72. Go to original source... Go to PubMed...
    22. Saller R, Pfister-Hotz G, Iten F, et al. Iberogast: a modern phytotherapeutic combined herbal drug for the treatment of functional disorders of the gastrointestinal tract (dyspepsia, irritable bowel syndrome)-from phytomedicine to ''evidence based phytotherapy''. A systematic review. Forsch. Komplementaermed. 2002; 9; 1-20.
    23. Navrátil V, Dvoran P, Ďurana V, et al. Je funkčná dyspepsia skutočne tak častá?. Vnitrni lekarstvi. 2018; 64: 903-910. Go to original source... Go to PubMed...

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