Pediatr. praxi. 2023;24(6):411-415 | DOI: 10.36290/ped.2023.099

Juvenile spondyloarthritis/sacroiliitis (previously known as Bechterev´s disease) with focus on early diagnostics and therapy - case reports and summary for clinical practice

doc. MUDr. Kateřina Bouchalová, Ph.D.1, MUDr. Lenka Frydrychová1, MUDr. Veronika Moškořová1, MUDr. Zuzana Pytelová1, MUDr. Jakub Čivrný2
1 Dětská klinika, LF UP a FN Olomouc
2 Radiologická klinika, FN Olomouc

An article is focused on juvenile spondyloarthritis (JSpA) (previously Bechterev´s disease) in childhood. The disease is included in enthesitis-related arthritis (ERA) subgroup of JIA based on currently used classification. Differential diagnostics with stress on early diagnosis and therapy is described. It is also reviewed how general practitioners might contribute. Case reports of children with spondyloarthritis as a main symptom of ERA are presented. A back pain might be the first, and only symptom of ERA. In some patients peripheral arthritis or enthesitis are found. A proportion of patients suffers from uveitis. Here described patients reached remission using adalimumab, however one relapsed early. Unfortunately, early relapses in ERA subgroup of JIA are frequent after therapy termination. An early diagnosis is a clue to successful therapy.

Keywords: arthritis, juvenile spondyloarthritis, enthesitis-related arthritis, disease, juvenile idiopathic arthritis, differential diagnosis, methotrexate, biological therapy, adalimumab.

Accepted: November 14, 2023; Published: November 22, 2023  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Bouchalová K, Frydrychová L, Moškořová V, Pytelová Z, Čivrný J. Juvenile spondyloarthritis/sacroiliitis (previously known as Bechterev´s disease) with focus on early diagnostics and therapy - case reports and summary for clinical practice. Pediatr. praxi. 2023;24(6):411-415. doi: 10.36290/ped.2023.099.
Download citation

References

  1. Petty RE, Laxer RM, Wedderburn LR. Juvenile Idiopathic Arthritis. In: Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: p. 209-215.
  2. Tse SML, Colbert RA. Enthesitis-Related Arthritis. In: Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: p. 250-267.
  3. Bouchalová K, Flogelová H, Pytelová Z, et al. Diferenciální diagnostika artralgií a artritid - diagnostické možnosti v ambulanci praktického lékaře pro děti a dorost - kazuistiky a shrnutí pro praxi. Pediatr. praxi. 2023;24(3):179-185. Go to original source...
  4. Zemel L, Bockenstedt LK. Lyme Disease. In: Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: p. 602-612.
  5. LeBlanc CMA, Houghton KM. Noninflammatory Musculoskeletal Pain. In: Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: p. 665-683.
  6. Sherry DD, Clinch J. Pain Amplification Syndromes. In Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: 702-713.
  7. Ricciuto A, Griffiths AM, Laxer RM. Musculosceletal Manifestations of Inflammatory Bowel Disease. In: Petty RE, Laxer RM, Lindsley CB, et al. Textbook of Pediatric Rheumatology. Philadelphia: Elsevier Books; 2021: p. 684-690.
  8. Doležalová P, Hoza J. Diferenciální diagnostika artritidy v dětském věku. In: Lebl J, et al. Klinická pediatrie. Praha: Galén; 2012: p. 253-260.
  9. Burešová J, Doležalová P, Hoza J, et al. Nezánětlivá onemocnění kloubů, kostí a pojiva. In: Doležalová P, Dallos T. Dětská revmatologie v praxi. 1. vyd. Praha: Mladá fronta; 2019: p. 142-176.
  10. Malcová H. Muskuloskeletální manifestace nerevmatických onemocnění. In: Doležalová P, Dallos T. Dětská revmatologie v praxi. 1. vyd. Praha: Mladá fronta; 2019: p. 177-195.
  11. Bouchalová K, Čelková M. Juvenilní idiopatická artritida. In: Zadražil J, Horak P, Karasek D. Moderní farmakoterapie autoimunitních chorob. Praha: Maxdorf; 2019: p. 132-140.
  12. Vargová V. Juvenilná idiopatická artritida. In: Doležalová P, Dallos T. Dětská revmatologie v praxi. Praha: Mladá fronta; 2019:209-223.
  13. Vrtíková E. Bolesti chrbta a skolióza. In: Doležalová P, Dallos T. Dětská revmatologie v praxi. Praha: Mladá fronta; 2019:365-378.
  14. Bouchalová K, Fráňová J, Schüller M, et al. Chronická rekurentní multifokální osteomyelitida (CRMO) v dětském věku - přehled a vlastní výsledky. Čes. Revmatol. 2019;27(3):116-124.
  15. Chausset A, Lambert C, Belot A, et al. Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study. Pediatr Rheumatol Online J. 2023;21(1):24. Go to original source... Go to PubMed...
  16. Rezaei E, Hogan D, Trost B, et al. Clinical and associated inflammatory biomarker features predictive of short-term outcomes in non-systemic juvenile idiopathic arthritis. Rheumatology (Oxford). 2020;59(9):2402-2411. Go to original source... Go to PubMed...
  17. Informace o dětských revmatických onemocněních [online]. ©2016. [cit. 9-9-2023]. Available from: http://www.printo.it/pediatric-rheumatology/.




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.