Pediatr. praxi. 2025;26(4):212-215 | DOI: 10.36290/ped.2025.041

Mucociliary clearance in the context of respiratory disease treatment: effects of commonly used medications

MUDr. Patrícia Čelková, MUDr. Pavol Dvoran, PhD., prof. MUDr. Peter Bánovčin, CSc., prof. MUDr. Miloš Jeseňák, PhD., MBA, Dott.Ric., MHA
Klinika detí a dorastu, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave, Univerzitná nemocnica Martin

Mucociliary clearance is an essential airway defence mechanism that plays a key role in the removal of mucus and pollutants from the respiratory tract. Its function can be affected by a wide range of drugs, including those commonly used in the treatment of respiratory diseases. This review summarizes the current knowledge on their effects on airway cilia activity and efficiency of mucociliary transport, taking into account the differences between drug groups and routes of administration. The aim is to highlight the relevance of these effects for clinical practice and to aid the correct choice of treatment in patients with airway diseases.

Keywords: mucociliary clearance, motile cilia, respiratory diseases, topical therapy.

Accepted: August 20, 2025; Published: September 26, 2025  Show citation

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Čelková P, Dvoran P, Bánovčin P, Jeseňák Dott. Ric M. Mucociliary clearance in the context of respiratory disease treatment: effects of commonly used medications. Pediatr. praxi. 2025;26(4):212-215. doi: 10.36290/ped.2025.041.
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